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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ICAL_HUMAN (P20810)

Summary

This is the summary of UniProt entry ICAL_HUMAN (P20810).

Description: Calpastatin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 708 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 199
Pfam A Calpain_inhib 119 224
low_complexity n/a 127 132
low_complexity n/a 163 181
disorder n/a 201 708
Pfam A Calpain_inhib 232 359
low_complexity n/a 313 327
low_complexity n/a 350 375
Pfam A Calpain_inhib 369 501
low_complexity n/a 382 402
coiled_coil n/a 455 475
low_complexity n/a 463 475
Pfam A Calpain_inhib 512 639
low_complexity n/a 561 578
low_complexity n/a 672 693

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P20810. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNPTETKAIP VSQQMEGPHL PNKKKHKKQA VKTEPEKKSQ STKLSVVHEK
50
51
KSQEGKPKEH TEPKSLPKQA SDTGSNDAHN KKAVSRSAEQ QPSEKSTEPK
100
101
TKPQDMISAG GESVAGITAI SGKPGDKKKE KKSLTPAVPV ESKPDKPSGK
150
151
SGMDAALDDL IDTLGGPEET EEENTTYTGP EVSDPMSSTY IEELGKREVT
200
201
IPPKYRELLA KKEGITGPPA DSSKPIGPDD AIDALSSDFT CGSPTAAGKK
250
251
TEKEESTEVL KAQSAGTVRS AAPPQEKKRK VEKDTMSDQA LEALSASLGT
300
301
RQAEPELDLR SIKEVDEAKA KEEKLEKCGE DDETIPSEYR LKPATDKDGK
350
351
PLLPEPEEKP KPRSESELID ELSEDFDRSE CKEKPSKPTE KTEESKAAAP
400
401
APVSEAVCRT SMCSIQSAPP EPATLKGTVP DDAVEALADS LGKKEADPED
450
451
GKPVMDKVKE KAKEEDREKL GEKEETIPPD YRLEEVKDKD GKPLLPKESK
500
501
EQLPPMSEDF LLDALSEDFS GPQNASSLKF EDAKLAAAIS EVVSQTPAST
550
551
TQAGAPPRDT SQSDKDLDDA LDKLSDSLGQ RQPDPDENKP MEDKVKEKAK
600
601
AEHRDKLGER DDTIPPEYRH LLDDNGQDKP VKPPTKKSED SKKPADDQDP
650
651
IDALSGDLDS CPSTTETSQN TAKDKCKKAA SSSKAPKNGG KAKDSAKTTE
700
701
ETSKPKDD                                              
708
 

Show the unformatted sequence.

Checksums:
CRC64:2DB0C14B860E89C7
MD5:2e35295d86b1ab26dc6127bdc6fc003f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.