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20  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RIR1_YEAST (P21524)

Summary

This is the summary of UniProt entry RIR1_YEAST (P21524).

Description: Ribonucleoside-diphosphate reductase large chain 1 EC=1.17.4.1
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 888 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A ATP-cone 1 89
Pfam A Ribonuc_red_lgN 141 213
Pfam A Ribonuc_red_lgC 215 743
disorder n/a 771 772
low_complexity n/a 777 789
disorder n/a 803 861
low_complexity n/a 803 819

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P21524. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MYVYKRDGRK EPVQFDKITA RISRLCYGLD PKHIDAVKVT QRIISGVYEG
50
51
VTTIELDNLA AETCAYMTTV HPDYATLAAR IAISNLHKQT TKQFSKVVED
100
101
LYRYVNAATG KPAPMISDDV YNIVMENKDK LNSAIVYDRD FQYSYFGFKT
150
151
LERSYLLRIN GQVAERPQHL IMRVALGIHG RDIEAALETY NLMSLKYFTH
200
201
ASPTLFNAGT PKPQMSSCFL VAMKEDSIEG IYDTLKECAL ISKTAGGIGL
250
251
HIHNIRSTGS YIAGTNGTSN GLIPMIRVFN NTARYVDQGG NKRPGAFALY
300
301
LEPWHADIFD FIDIRKNHGK EEIRARDLFP ALWIPDLFMK RVEENGTWTL
350
351
FSPTSAPGLS DCYGDEFEAL YTRYEKEGRG KTIKAQKLWY SILEAQTETG
400
401
TPFVVYKDAC NRKSNQKNLG VIKSSNLCCE IVEYSAPDET AVCNLASVAL
450
451
PAFIETSEDG KTSTYNFKKL HEIAKVVTRN LNRVIDRNYY PVEEARKSNM
500
501
RHRPIALGVQ GLADTFMLLR LPFDSEEARL LNIQIFETIY HASMEASCEL
550
551
AQKDGPYETF QGSPASQGIL QFDMWDQKPY GMWDWDTLRK DIMKHGVRNS
600
601
LTMAPMPTAS TSQILGYNEC FEPVTSNMYS RRVLSGEFQV VNPYLLRDLV
650
651
DLGIWDEGMK QYLITQNGSI QGLPNVPQEL KDLYKTVWEI SQKTIINMAA
700
701
DRSVYIDQSH SLNLFLRAPT MGKLTSMHFY GWKKGLKTGM YYLRTQAASA
750
751
AIQFTIDQKI ADQATENVAD ISNLKRPSYM PSSASYAASD FVPAAVTANA
800
801
TIPSLDSSSE ASREASPAPT GSHSLTKGMA ELNVQESKVE VPEVPAPTKN
850
851
EEKAAPIVDD EETEFDIYNS KVIACAIDNP EACEMCSG             
888
 

Show the unformatted sequence.

Checksums:
CRC64:56BE1B077916E419
MD5:102901a9ce57251b69bf7a9db1b4bd7e

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ATP-cone 1 - 89 3PAW A 1 - 89 Jmol AstexViewer SPICE
B 1 - 89 Jmol AstexViewer SPICE
C 1 - 89 Jmol AstexViewer SPICE
D 1 - 89 Jmol AstexViewer SPICE
15 - 89 1ZYZ A 15 - 89 Jmol AstexViewer SPICE
B 15 - 89 Jmol AstexViewer SPICE
74 - 89 3S8C A 74 - 89 Jmol AstexViewer SPICE
76 - 89 2CVS A 76 - 89 Jmol AstexViewer SPICE
2CVT A 76 - 89 Jmol AstexViewer SPICE
2CVX A 76 - 89 Jmol AstexViewer SPICE
2ZLF A 76 - 89 Jmol AstexViewer SPICE
2ZLG A 76 - 89 Jmol AstexViewer SPICE
3S87 A 76 - 89 Jmol AstexViewer SPICE
3S8A A 76 - 89 Jmol AstexViewer SPICE
78 - 89 3TBA A 78 - 89 Jmol AstexViewer SPICE
80 - 89 3S8B A 80 - 89 Jmol AstexViewer SPICE
Ribonuc_red_lgC 215 - 743 1ZYZ A 215 - 743 Jmol AstexViewer SPICE
B 215 - 743 Jmol AstexViewer SPICE
1ZZD A 215 - 743 Jmol AstexViewer SPICE
2CVS A 215 - 743 Jmol AstexViewer SPICE
2CVT A 215 - 743 Jmol AstexViewer SPICE
2CVU A 215 - 743 Jmol AstexViewer SPICE
2CVV A 215 - 743 Jmol AstexViewer SPICE
2CVW A 215 - 743 Jmol AstexViewer SPICE
2CVX A 215 - 743 Jmol AstexViewer SPICE
2CVY A 215 - 743 Jmol AstexViewer SPICE
2EUD A 215 - 743 Jmol AstexViewer SPICE
2ZLF A 215 - 743 Jmol AstexViewer SPICE
2ZLG A 215 - 743 Jmol AstexViewer SPICE
3K8T A 215 - 743 Jmol AstexViewer SPICE
3PAW A 215 - 743 Jmol AstexViewer SPICE
B 215 - 743 Jmol AstexViewer SPICE
C 215 - 743 Jmol AstexViewer SPICE
D 215 - 743 Jmol AstexViewer SPICE
3S87 A 215 - 743 Jmol AstexViewer SPICE
3S8A A 215 - 743 Jmol AstexViewer SPICE
3S8B A 215 - 743 Jmol AstexViewer SPICE
3S8C A 215 - 743 Jmol AstexViewer SPICE
3TB9 A 215 - 743 Jmol AstexViewer SPICE
3TBA A 215 - 743 Jmol AstexViewer SPICE
Ribonuc_red_lgN 141 - 213 1ZYZ A 141 - 213 Jmol AstexViewer SPICE
B 141 - 213 Jmol AstexViewer SPICE
1ZZD A 141 - 213 Jmol AstexViewer SPICE
2CVS A 141 - 213 Jmol AstexViewer SPICE
2CVT A 141 - 213 Jmol AstexViewer SPICE
2CVU A 141 - 213 Jmol AstexViewer SPICE
2CVV A 141 - 213 Jmol AstexViewer SPICE
2CVW A 141 - 213 Jmol AstexViewer SPICE
2CVX A 141 - 213 Jmol AstexViewer SPICE
2CVY A 141 - 213 Jmol AstexViewer SPICE
2EUD A 141 - 213 Jmol AstexViewer SPICE
2ZLF A 141 - 213 Jmol AstexViewer SPICE
2ZLG A 141 - 213 Jmol AstexViewer SPICE
3K8T A 141 - 213 Jmol AstexViewer SPICE
3PAW A 141 - 213 Jmol AstexViewer SPICE
B 141 - 213 Jmol AstexViewer SPICE
C 141 - 213 Jmol AstexViewer SPICE
D 141 - 213 Jmol AstexViewer SPICE
3S87 A 141 - 213 Jmol AstexViewer SPICE
3S8A A 141 - 213 Jmol AstexViewer SPICE
3S8B A 141 - 213 Jmol AstexViewer SPICE
3S8C A 141 - 213 Jmol AstexViewer SPICE
3TB9 A 141 - 213 Jmol AstexViewer SPICE
3TBA A 141 - 213 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.