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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TGM2_HUMAN (P21980)

Summary

This is the summary of UniProt entry TGM2_HUMAN (P21980).

Description: Protein-glutamine gamma-glutamyltransferase 2 EC=2.3.2.13
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 687 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Transglut_N 5 124
disorder n/a 73 76
low_complexity n/a 187 198
Pfam A Transglut_core 256 359
disorder n/a 352 358
disorder n/a 436 447
disorder n/a 456 461
Pfam A Transglut_C 473 573
Pfam A Transglut_C 587 686
disorder n/a 635 636

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P21980. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEELVLERC DLELETNGRD HHTADLCREK LVVRRGQPFW LTLHFEGRNY
50
51
EASVDSLTFS VVTGPAPSQE AGTKARFPLR DAVEEGDWTA TVVDQQDCTL
100
101
SLQLTTPANA PIGLYRLSLE ASTGYQGSSF VLGHFILLFN AWCPADAVYL
150
151
DSEEERQEYV LTQQGFIYQG SAKFIKNIPW NFGQFEDGIL DICLILLDVN
200
201
PKFLKNAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGVS
250
251
PMSWIGSVDI LRRWKNHGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN
300
301
YNSAHDQNSN LLIEYFRNEF GEIQGDKSEM IWNFHCWVES WMTRPDLQPG
350
351
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD
400
401
VVDWIQQDDG SVHKSINRSL IVGLKISTKS VGRDEREDIT HTYKYPEGSS
450
451
EEREAFTRAN HLNKLAEKEE TGMAMRIRVG QSMNMGSDFD VFAHITNNTA
500
501
EEYVCRLLLC ARTVSYNGIL GPECGTKYLL NLNLEPFSEK SVPLCILYEK
550
551
YRDCLTESNL IKVRALLVEP VINSYLLAER DLYLENPEIK IRILGEPKQK
600
601
RKLVAEVSLQ NPLPVALEGC TFTVEGAGLT EEQKTVEIPD PVEAGEEVKV
650
651
RMDLLPLHMG LHKLVVNFES DKLKAVKGFR NVIIGPA              
687
 

Show the unformatted sequence.

Checksums:
CRC64:7DA33FF335DE7B37
MD5:8cee5f043edad9e8ef862ed9ab09ef31

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Transglut_C 473 - 573 1KV3 A 473 - 573 Jmol AstexViewer SPICE
B 473 - 573 Jmol AstexViewer SPICE
C 473 - 573 Jmol AstexViewer SPICE
D 473 - 573 Jmol AstexViewer SPICE
E 473 - 573 Jmol AstexViewer SPICE
F 473 - 573 Jmol AstexViewer SPICE
2Q3Z A 473 - 573 Jmol AstexViewer SPICE
3LY6 A 473 - 573 Jmol AstexViewer SPICE
B 473 - 573 Jmol AstexViewer SPICE
C 473 - 573 Jmol AstexViewer SPICE
3S3J A 473 - 573 Jmol AstexViewer SPICE
3S3P A 473 - 573 Jmol AstexViewer SPICE
3S3S A 473 - 573 Jmol AstexViewer SPICE
587 - 683 2Q3Z A 587 - 683 Jmol AstexViewer SPICE
3S3P A 587 - 683 Jmol AstexViewer SPICE
3S3S A 587 - 683 Jmol AstexViewer SPICE
587 - 685 3S3J A 587 - 685 Jmol AstexViewer SPICE
587 - 686 1KV3 A 587 - 686 Jmol AstexViewer SPICE
B 587 - 686 Jmol AstexViewer SPICE
C 587 - 686 Jmol AstexViewer SPICE
D 587 - 686 Jmol AstexViewer SPICE
E 587 - 686 Jmol AstexViewer SPICE
F 587 - 686 Jmol AstexViewer SPICE
3LY6 A 587 - 686 Jmol AstexViewer SPICE
B 587 - 686 Jmol AstexViewer SPICE
C 587 - 686 Jmol AstexViewer SPICE
Transglut_core 256 - 359 1KV3 A 256 - 359 Jmol AstexViewer SPICE
B 256 - 359 Jmol AstexViewer SPICE
C 256 - 359 Jmol AstexViewer SPICE
D 256 - 359 Jmol AstexViewer SPICE
E 256 - 359 Jmol AstexViewer SPICE
F 256 - 359 Jmol AstexViewer SPICE
2Q3Z A 256 - 359 Jmol AstexViewer SPICE
3LY6 A 256 - 359 Jmol AstexViewer SPICE
B 256 - 359 Jmol AstexViewer SPICE
C 256 - 359 Jmol AstexViewer SPICE
3S3J A 256 - 359 Jmol AstexViewer SPICE
3S3P A 256 - 359 Jmol AstexViewer SPICE
3S3S A 256 - 359 Jmol AstexViewer SPICE
Transglut_N 15 - 122 1KV3 A 15 - 122 Jmol AstexViewer SPICE
B 15 - 122 Jmol AstexViewer SPICE
C 15 - 122 Jmol AstexViewer SPICE
D 15 - 122 Jmol AstexViewer SPICE
E 15 - 122 Jmol AstexViewer SPICE
F 15 - 122 Jmol AstexViewer SPICE
5 - 124 2Q3Z A 5 - 124 Jmol AstexViewer SPICE
3LY6 A 5 - 124 Jmol AstexViewer SPICE
B 5 - 124 Jmol AstexViewer SPICE
C 5 - 124 Jmol AstexViewer SPICE
3S3J A 5 - 124 Jmol AstexViewer SPICE
3S3P A 5 - 124 Jmol AstexViewer SPICE
3S3S A 5 - 124 Jmol AstexViewer SPICE