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10  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GSTM2_HUMAN (P28161)

Summary

This is the summary of UniProt entry GSTM2_HUMAN (P28161).

Description: Glutathione S-transferase Mu 2 EC=2.5.1.18
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 218 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A GST_N 3 82
Pfam A GST_C 104 192

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P28161. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPMTLGYWNI RGLAHSIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK
50
51
FKLGLDFPNL PYLIDGTHKI TQSNAILRYI ARKHNLCGES EKEQIREDIL
100
101
ENQFMDSRMQ LAKLCYDPDF EKLKPEYLQA LPEMLKLYSQ FLGKQPWFLG
150
151
DKITFVDFIA YDVLERNQVF EPSCLDAFPN LKDFISRFEG LEKISAYMKS
200
201
SRFLPRPVFT KMAVWGNK                                   
218
 

Show the unformatted sequence.

Checksums:
CRC64:15203709D4A63789
MD5:b855a9825c263bbe987ddd00a513b233

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
GST_C 104 - 192 1HNA A 103 - 191 Jmol AstexViewer SPICE
1HNB A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
1HNC A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
C 103 - 191 Jmol AstexViewer SPICE
D 103 - 191 Jmol AstexViewer SPICE
1XW5 A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
1YKC A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
2AB6 A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
C 103 - 191 Jmol AstexViewer SPICE
D 103 - 191 Jmol AstexViewer SPICE
2C4J A 104 - 192 Jmol AstexViewer SPICE
B 104 - 192 Jmol AstexViewer SPICE
C 104 - 192 Jmol AstexViewer SPICE
D 104 - 192 Jmol AstexViewer SPICE
2GTU A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
3GTU A 103 - 191 Jmol AstexViewer SPICE
C 103 - 191 Jmol AstexViewer SPICE
3GUR A 103 - 191 Jmol AstexViewer SPICE
B 103 - 191 Jmol AstexViewer SPICE
C 103 - 191 Jmol AstexViewer SPICE
D 103 - 191 Jmol AstexViewer SPICE
GST_N 3 - 82 1HNA A 2 - 81 Jmol AstexViewer SPICE
1HNB A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
1HNC A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
C 2 - 81 Jmol AstexViewer SPICE
D 2 - 81 Jmol AstexViewer SPICE
1XW5 A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
1YKC A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
2AB6 A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
C 2 - 81 Jmol AstexViewer SPICE
D 2 - 81 Jmol AstexViewer SPICE
2C4J A 3 - 82 Jmol AstexViewer SPICE
B 3 - 82 Jmol AstexViewer SPICE
C 3 - 82 Jmol AstexViewer SPICE
D 3 - 82 Jmol AstexViewer SPICE
2GTU A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
3GTU A 2 - 81 Jmol AstexViewer SPICE
C 2 - 81 Jmol AstexViewer SPICE
3GUR A 2 - 81 Jmol AstexViewer SPICE
B 2 - 81 Jmol AstexViewer SPICE
C 2 - 81 Jmol AstexViewer SPICE
D 2 - 81 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.