Summary
This is the summary of UniProt entry ERCC5_HUMAN (P28715).
| Description: | DNA repair protein complementing XP-G cells EC=3.1.-.- |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1186 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | XPG_N | 1 | 98 |
| disorder | n/a | 94 | 97 |
| disorder | n/a | 100 | 101 |
| low_complexity | n/a | 104 | 115 |
| disorder | n/a | 130 | 131 |
| disorder | n/a | 145 | 174 |
| low_complexity | n/a | 150 | 167 |
| disorder | n/a | 176 | 181 |
| disorder | n/a | 187 | 188 |
| disorder | n/a | 190 | 193 |
| disorder | n/a | 204 | 207 |
| disorder | n/a | 215 | 220 |
| disorder | n/a | 245 | 269 |
| Pfam B | Pfam-B_29308 | 261 | 401 |
| disorder | n/a | 273 | 278 |
| disorder | n/a | 301 | 392 |
| low_complexity | n/a | 352 | 364 |
| disorder | n/a | 394 | 397 |
| disorder | n/a | 399 | 549 |
| disorder | n/a | 553 | 557 |
| low_complexity | n/a | 557 | 565 |
| disorder | n/a | 560 | 595 |
| disorder | n/a | 600 | 606 |
| disorder | n/a | 608 | 732 |
| low_complexity | n/a | 642 | 656 |
| low_complexity | n/a | 732 | 757 |
| coiled_coil | n/a | 733 | 756 |
| disorder | n/a | 744 | 748 |
| disorder | n/a | 755 | 757 |
| Pfam A | XPG_I | 777 | 861 |
| disorder | n/a | 903 | 912 |
| Pfam B | Pfam-B_659 | 989 | 1097 |
| disorder | n/a | 1008 | 1009 |
| low_complexity | n/a | 1025 | 1042 |
| disorder | n/a | 1051 | 1052 |
| disorder | n/a | 1056 | 1076 |
| low_complexity | n/a | 1064 | 1079 |
| low_complexity | n/a | 1094 | 1109 |
| disorder | n/a | 1095 | 1186 |
| low_complexity | n/a | 1146 | 1154 |
| low_complexity | n/a | 1171 | 1185 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P28715. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MGVQGLWKLL ECSGRQVSPE ALEGKILAVD ISIWLNQALK GVRDRHGNSI
50 51
ENPHLLTLFH RLCKLLFFRI RPIFVFDGDA PLLKKQTLVK RRQRKDLASS
100 101
DSRKTTEKLL KTFLKRQAIK TAFRSKRDEA LPSLTQVRRE NDLYVLPPLQ
150 151
EEEKHSSEEE DEKEWQERMN QKQALQEEFF HNPQAIDIES EDFSSLPPEV
200 201
KHEILTDMKE FTKRRRTLFE AMPEESDDFS QYQLKGLLKK NYLNQHIEHV
250 251
QKEMNQQHSG HIRRQYEDEG GFLKEVESRR VVSEDTSHYI LIKGIQAKTV
300 301
AEVDSESLPS SSKMHGMSFD VKSSPCEKLK TEKEPDATPP SPRTLLAMQA
350 351
ALLGSSSEEE LESENRRQAR GRNAPAAVDE GSISPRTLSA IKRALDDDED
400 401
VKVCAGDDVQ TGGPGAEEMR INSSTENSDE GLKVRDGKGI PFTATLASSS
450 451
VNSAEEHVAS TNEGREPTDS VPKEQMSLVH VGTEAFPISD ESMIKDRKDR
500 501
LPLESAVVRH SDAPGLPNGR ELTPASPTCT NSVSKNETHA EVLEQQNELC
550 551
PYESKFDSSL LSSDDETKCK PNSASEVIGP VSLQETSSIV SVPSEAVDNV
600 601
ENVVSFNAKE HENFLETIQE QQTTESAGQD LISIPKAVEP MEIDSEESES
650 651
DGSFIEVQSV ISDEELQAEF PETSKPPSEQ GEEELVGTRE GEAPAESESL
700 701
LRDNSERDDV DGEPQEAEKD AEDSLHEWQD INLEELETLE SNLLAQQNSL
750 751
KAQKQQQERI AATVTGQMFL ESQELLRLFG IPYIQAPMEA EAQCAILDLT
800 801
DQTSGTITDD SDIWLFGARH VYRNFFNKNK FVEYYQYVDF HNQLGLDRNK
850 851
LINLAYLLGS DYTEGIPTVG CVTAMEILNE FPGHGLEPLL KFSEWWHEAQ
900 901
KNPKIRPNPH DTKVKKKLRT LQLTPGFPNP AVAEAYLKPV VDDSKGSFLW
950 951
GKPDLDKIRE FCQRYFGWNR TKTDESLFPV LKQLDAQQTQ LRIDSFFRLA
1000 1001
QQEKEDAKRI KSQRLNRAVT CMLRKEKEAA ASEIEAVSVA MEKEFELLDK
1050 1051
AKGKTQKRGI TNTLEESSSL KRKRLSDSKG KNTCGGFLGE TCLSESSDGS
1100 1101
SSEDAESSSL MNVQRRTAAK EPKTSASDSQ NSVKEAPVKN GGATTSSSSD
1150 1151
SDDDGGKEKM VLVTARSVFG KKRRKLRRAR GRKRKT
1186
Show the unformatted sequence. |
| Checksums: |
CRC64:B0A844D617C53F2E
MD5:c3bed7beb423e4b264904487e4d21bb8
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.