Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TF2B_YEAST (P29055)

Summary

This is the summary of UniProt entry TF2B_YEAST (P29055).

Description: Transcription initiation factor IIB
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 345 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 10
Pfam A TF_Zn_Ribbon 22 66
disorder n/a 63 86
disorder n/a 90 94
disorder n/a 103 110
disorder n/a 112 114
disorder n/a 117 118
Pfam A TFIIB 133 203
Pfam A TFIIB 239 309

Show or hide domain scores.

Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

Note: it can take a few seconds for this image to be generated and loaded.

Loading feature alignment...

Show sources update panel.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P29055. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMTRESIDKR AGRRGPNLNI VLTCPECKVY PPKIVERFSE GDVVCALCGL
50
51
VLSDKLVDTR SEWRTFSNDD HNGDDPSRVG EASNPLLDGN NLSTRIGKGE
100
101
TTDMRFTKEL NKAQGKNVMD KKDNEVQAAF AKITMLCDAA ELPKIVKDCA
150
151
KEAYKLCHDE KTLKGKSMES IMAASILIGC RRAEVARTFK EIQSLIHVKT
200
201
KEFGKTLNIM KNILRGKSED GFLKIDTDNM SGAQNLTYIP RFCSHLGLPM
250
251
QVTTSAEYTA KKCKEIKEIA GKSPITIAVV SIYLNILLFQ IPITAAKVGQ
300
301
TLQVTEGTIK SGYKILYEHR DKLVDPQLIA NGVVSLDNLP GVEKK     
345
 

Show the unformatted sequence.

Checksums:
CRC64:8F1F6D24602436E2
MD5:8caea450ad754bffde7626fd4e55f2af

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
TF_Zn_Ribbon 22 - 66 3K1F M 22 - 66 Jmol AstexViewer SPICE
3K7A M 22 - 66 Jmol AstexViewer SPICE
TFIIB 133 - 203 3K7A M 133 - 203 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.