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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PTN6_HUMAN (P29350)

Summary

This is the summary of UniProt entry PTN6_HUMAN (P29350).

Description: Tyrosine-protein phosphatase non-receptor type 6 EC=3.1.3.48
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 595 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A SH2 4 79
Pfam A SH2 110 194
disorder n/a 228 232
disorder n/a 257 268
Pfam A Y_phosphatase 270 514
disorder n/a 273 276
disorder n/a 536 595

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P29350. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVRWFHRDLS GLDAETLLKG RGVHGSFLAR PSRKNQGDFS LSVRVGDQVT
50
51
HIRIQNSGDF YDLYGGEKFA TLTELVEYYT QQQGVLQDRD GTIIHLKYPL
100
101
NCSDPTSERW YHGHMSGGQA ETLLQAKGEP WTFLVRESLS QPGDFVLSVL
150
151
SDQPKAGPGS PLRVTHIKVM CEGGRYTVGG LETFDSLTDL VEHFKKTGIE
200
201
EASGAFVYLR QPYYATRVNA ADIENRVLEL NKKQESEDTA KAGFWEEFES
250
251
LQKQEVKNLH QRLEGQRPEN KGKNRYKNIL PFDHSRVILQ GRDSNIPGSD
300
301
YINANYIKNQ LLGPDENAKT YIASQGCLEA TVNDFWQMAW QENSRVIVMT
350
351
TREVEKGRNK CVPYWPEVGM QRAYGPYSVT NCGEHDTTEY KLRTLQVSPL
400
401
DNGDLIREIW HYQYLSWPDH GVPSEPGGVL SFLDQINQRQ ESLPHAGPII
450
451
VHCSAGIGRT GTIIVIDMLM ENISTKGLDC DIDIQKTIQM VRAQRSGMVQ
500
501
TEAQYKFIYV AIAQFIETTK KKLEVLQSQK GQESEYGNIT YPPAMKNAHA
550
551
KASRTSSKHK EDVYENLHTK NKREEKVKKQ RSADKEKSKG SLKRK     
595
 

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Checksums:
CRC64:4D7736C21D3542D2
MD5:2ca921a3d628c01bd113424ca56d1d5a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SH2 110 - 194 1X6C A 8 - 92 Jmol AstexViewer SPICE
2B3O A 110 - 194 Jmol AstexViewer SPICE
2RMX A 8 - 92 Jmol AstexViewer SPICE
2YU7 A 8 - 92 Jmol AstexViewer SPICE
3PS5 A 110 - 194 Jmol AstexViewer SPICE
4 - 79 2B3O A 4 - 79 Jmol AstexViewer SPICE
3PS5 A 4 - 79 Jmol AstexViewer SPICE
Y_phosphatase 270 - 514 1FPR A 272 - 516 Jmol AstexViewer SPICE
1GWZ A 272 - 516 Jmol AstexViewer SPICE
2B3O A 270 - 514 Jmol AstexViewer SPICE
3PS5 A 270 - 514 Jmol AstexViewer SPICE