Summary
This is the summary of UniProt entry SC6A4_RAT (P31652).
| Description: | Sodium-dependent serotonin transporter |
| Source organism: |
Rattus norvegicus (Rat)
(NCBI taxonomy ID
10116)
View Pfam proteome data. |
| Length: | 630 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 3 |
| disorder | n/a | 6 | 14 |
| Pfam A | 5HT_transporter | 23 | 64 |
| disorder | n/a | 23 | 35 |
| disorder | n/a | 37 | 38 |
| disorder | n/a | 40 | 50 |
| Pfam A | SNF | 79 | 600 |
| transmembrane | n/a | 88 | 106 |
| transmembrane | n/a | 118 | 139 |
| transmembrane | n/a | 160 | 188 |
| transmembrane | n/a | 251 | 268 |
| transmembrane | n/a | 280 | 306 |
| transmembrane | n/a | 326 | 350 |
| transmembrane | n/a | 362 | 387 |
| transmembrane | n/a | 422 | 443 |
| transmembrane | n/a | 464 | 488 |
| low_complexity | n/a | 475 | 485 |
| transmembrane | n/a | 500 | 523 |
| transmembrane | n/a | 535 | 558 |
| transmembrane | n/a | 570 | 595 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P31652. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
METTPLNSQK VLSECKDRED CQENGVLQKG VPTTADRAEP SQISNGYSAV
50 51
PSTSAGDEAS HSIPAATTTL VAEIRQGERE TWGKKMDFLL SVIGYAVDLG
100 101
NIWRFPYICY QNGGGAFLLP YTIMAIFGGI PLFYMELALG QYHRNGCISI
150 151
WRKICPIFKG IGYAICIIAF YIASYYNTII AWALYYLISS LTDRLPWTSC
200 201
TNSWNTGNCT NYFAQDNITW TLHSTSPAEE FYLRHVLQIH QSKGLQDLGT
250 251
ISWQLTLCIV LIFTVIYFSI WKGVKTSGKV VWVTATFPYI VLSVLLVRGA
300 301
TLPGAWRGVV FYLKPNWQKL LETGVWVDAA AQIFFSLGPG FGVLLAFASY
350 351
NKFNNNCYQD ALVTSVVNCM TSFVSGFVIF TVLGYMAEMR NEDVSEVAKD
400 401
AGPSLLFITY AEAIANMPAS TFFAIIFFLM LITLGLDSTF AGLEGVITAV
450 451
LDEFPHIWAK RREWFVLIVV ITCVLGSLLT LTSGGAYVVT LLEEYATGPA
500 501
VLTVALIEAV AVSWFYGITQ FCSDVKEMLG FSPGWFWRIC WVAISPLFLL
550 551
FIICSFLMSP PQLRLFQYNY PHWSIVLGYC IGMSSVICIP TYIIYRLIST
600 601
PGTLKERIIK SITPETPTEI PCGDIRMNAV
630
Show the unformatted sequence. |
| Checksums: |
CRC64:44DA7C5888C403EE
MD5:56fc342f58c885215f65e0a811a15e3f
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.