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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PTP10_DROME (P35992)

Summary

This is the summary of UniProt entry PTP10_DROME (P35992).

Description: Tyrosine-protein phosphatase 10D EC=3.1.3.48
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
View Pfam proteome data.
Length: 1631 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 42
Pfam A fn3 124 206
disorder n/a 127 128
disorder n/a 210 212
Pfam A fn3 218 304
disorder n/a 260 267
disorder n/a 275 278
Pfam A fn3 313 395
disorder n/a 354 357
Pfam A fn3 406 488
low_complexity n/a 450 463
Pfam A fn3 496 575
disorder n/a 530 537
disorder n/a 541 547
disorder n/a 577 579
disorder n/a 581 582
Pfam A fn3 584 662
disorder n/a 614 615
disorder n/a 629 633
disorder n/a 637 640
disorder n/a 642 645
disorder n/a 661 671
Pfam A fn3 673 759
disorder n/a 674 676
disorder n/a 714 723
disorder n/a 775 777
Pfam A fn3 781 854
disorder n/a 786 793
Pfam A fn3 864 940
disorder n/a 867 868
low_complexity n/a 938 950
disorder n/a 958 966
Pfam A fn3 959 1044
disorder n/a 975 976
disorder n/a 1049 1055
Pfam B Pfam-B_20913 1062 1132
Pfam B Pfam-B_25005 1143 1182
transmembrane n/a 1198 1219
low_complexity n/a 1198 1217
low_complexity n/a 1220 1231
disorder n/a 1229 1234
disorder n/a 1237 1241
low_complexity n/a 1267 1278
Pfam A Y_phosphatase 1296 1526
disorder n/a 1326 1327
disorder n/a 1535 1556
disorder n/a 1558 1561
disorder n/a 1563 1569
disorder n/a 1572 1577
low_complexity n/a 1572 1589
disorder n/a 1579 1631
low_complexity n/a 1617 1622

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P35992. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLYQLSKATT RIRLKRQKAV PQHRWLWSLA FLAAFTLKDV RCADLAISIP
50
51
NNPGLDDGAS YRLDYSPPFG YPEPNTTIAS REIGDEIQFS RALPGTKYNF
100
101
WLYYTNFTHH DWLTWTVTIT TAPDPPSNLS VQVRSGKNAI ILWSPPTQGS
150
151
YTAFKIKVLG LSEASSSYNR TFQVNDNTFQ HSVKELTPGA TYQVQAYTIY
200
201
DGKESVAYTS RNFTTKPNTP GKFIVWFRNE TTLLVLWQPP YPAGIYTHYK
250
251
VSIEPPDAND SVLYVEKEGE PPGPAQAAFK GLVPGRAYNI SVQTMSEDEI
300
301
SLPTTAQYRT VPLRPLNVTF DRDFITSNSF RVLWEAPKGI SEFDKYQVSV
350
351
ATTRRQSTVP RSNEPVAFFD FRDIAEPGKT FNVIVKTVSG KVTSWPATGD
400
401
VTLRPLPVRN LRSINDDKTN TMIITWEADP ASTQDEYRIV YHELETFNGD
450
451
TSTLTTDRTR FTLESLLPGR NYSLSVQAVS KKMESNETSI FVVTRPSSPI
500
501
IEDLKSIRMG LNISWKSDVN SKQEQYEVLY SRNGTSDLRT QKTKESRLVI
550
551
KNLQPGAGYE LKVFAVSHDL RSEPHAYFQA VYPNPPRNMT IETVRSNSVL
600
601
VHWSPPESGE FTEYSIRYRT DSEQQWVRLP SVRSTEADIT DMTKGEKYTI
650
651
QVNTVSFGVE SPVPQEVNTT VPPNPVSNII QLVDSRNITL EWPKPEGRVE
700
701
SYILKWWPSD NPGRVQTKNV SENKSADDLS TVRVLIGELM PGVQYKFDIQ
750
751
TTSYGILSGI TSLYPRTMPL IQSDVVVANG EKEDERDTIT LSYTPTPQSS
800
801
SKFDIYRFSL GDAEIRDKEK LANDTDRKVT FTGLVPGRLY NITVWTVSGG
850
851
VASLPIQRQD RLYPEPITQL HATNITDTEI SLRWDLPKGE YNDFDIAYLT
900
901
ADNLLAQNMT TRNEITISDL RPHRNYTFTV VVRSGTESSV LRSSSPLSAS
950
951
FTTNEAVPGR VERFHPTDVQ PSEINFEWSL PSSEANGVIR QFSIAYTNIN
1000
1001
NLTDAGMQDF ESEEAFGVIK NLKPGETYVF KIQAKTAIGF GPEREYRQTM
1050
1051
PILAPPRPAT QVVPTEVYRS SSTIQIRFRK NYFSDQNGQV RMYTIIVAED
1100
1101
DAKNASGLEM PSWLDVQSYS VWLPYQAIDP YYPFENRSVE DFTIGTENCD
1150
1151
NHKIGYCNGP LKSGTTYRVK VRAFTGADKF TDTAYSFPIQ TDQDNTSLIV
1200
1201
AITVPLTIIL VLLVTLLFYK RRRNNCRKTT KDSRANDNMS LPDSVIEQNR
1250
1251
PILIKNFAEH YRLMSADSDF RFSEEFEELK HVGRDQPCTF ADLPCNRPKN
1300
1301
RFTNILPYDH SRFKLQPVDD DEGSDYINAN YVPGHNSPRE FIVTQGPLHS
1350
1351
TRDDFWRMCW ESNSRAIVML TRCFEKGREK CDQYWPNDTV PVFYGDIKVQ
1400
1401
ILNDSHYADW VMTEFMLCRG SEQRILRHFH FTTWPDFGVP NPPQTLVRFV
1450
1451
RAFRDRIGAE QRPIVVHCSA GVGRSGTFIT LDRILQQINT SDYVDIFGIV
1500
1501
YAMRKERVWM VQTEQQYICI HQCLLAVLEG KENIVGPARE MHDNEGYEGQ
1550
1551
QVQLDENGDV VATIEGHLSH HDLQQAEAEA IDDENAAILH DDQQPLTSSF
1600
1601
TGHHTHMPPT TSMSSFGGGG GGHTNVDAPD R                    
1631
 

Show the unformatted sequence.

Checksums:
CRC64:22A59AB61665875D
MD5:175e2cc80a525d2a33d91770bf348562

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Y_phosphatase 1296 - 1526 3S3E A 70 - 300 Jmol AstexViewer SPICE
B 70 - 300 Jmol AstexViewer SPICE
3S3F A 70 - 300 Jmol AstexViewer SPICE
B 70 - 300 Jmol AstexViewer SPICE
3S3H A 70 - 300 Jmol AstexViewer SPICE
B 70 - 300 Jmol AstexViewer SPICE
3S3K A 70 - 300 Jmol AstexViewer SPICE
B 70 - 300 Jmol AstexViewer SPICE