Summary
This is the summary of UniProt entry CDK9_HUMAN (P50750).
| Description: | Cyclin-dependent kinase 9 EC=2.7.11.22 EC=2.7.11.23 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 372 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Pkinase | 19 | 315 |
| disorder | n/a | 343 | 369 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P50750. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MAKQYDSVEC PFCDEVSKYE KLAKIGQGTF GEVFKARHRK TGQKVALKKV
50 51
LMENEKEGFP ITALREIKIL QLLKHENVVN LIEICRTKAS PYNRCKGSIY
100 101
LVFDFCEHDL AGLLSNVLVK FTLSEIKRVM QMLLNGLYYI HRNKILHRDM
150 151
KAANVLITRD GVLKLADFGL ARAFSLAKNS QPNRYTNRVV TLWYRPPELL
200 201
LGERDYGPPI DLWGAGCIMA EMWTRSPIMQ GNTEQHQLAL ISQLCGSITP
250 251
EVWPNVDNYE LYEKLELVKG QKRKVKDRLK AYVRDPYALD LIDKLLVLDP
300 301
AQRIDSDDAL NHDFFWSDPM PSDLKGMLST HLTSMFEYLA PPRRKGSQIT
350 351
QQSTNQSRNP ATTNQTEFER VF
372
Show the unformatted sequence. |
| Checksums: |
CRC64:69E851CC6F7A0388
MD5:2dec54fb2329f1ded5671e4a5c94123e
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Pkinase | 19 - 315 | 3BLH | A | 19 - 315 | Jmol AstexViewer SPICE |
| 3BLQ | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3BLR | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3LQ5 | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3MI9 | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3MIA | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3MY1 | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3TN8 | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3TNH | A | 19 - 315 | Jmol AstexViewer SPICE | ||
| 3TNI | A | 19 - 315 | Jmol AstexViewer SPICE |