Summary
This is the summary of UniProt entry KIF11_HUMAN (P52732).
| Description: | Kinesin-like protein KIF11 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1056 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 13 |
| Pfam A | Kinesin | 24 | 359 |
| disorder | n/a | 112 | 124 |
| disorder | n/a | 126 | 128 |
| disorder | n/a | 182 | 183 |
| disorder | n/a | 225 | 226 |
| disorder | n/a | 275 | 280 |
| low_complexity | n/a | 340 | 351 |
| coiled_coil | n/a | 368 | 402 |
| coiled_coil | n/a | 412 | 439 |
| disorder | n/a | 447 | 468 |
| coiled_coil | n/a | 447 | 474 |
| coiled_coil | n/a | 485 | 505 |
| Pfam B | Pfam-B_10018 | 491 | 581 |
| disorder | n/a | 495 | 499 |
| disorder | n/a | 510 | 511 |
| disorder | n/a | 514 | 522 |
| disorder | n/a | 797 | 799 |
| disorder | n/a | 804 | 807 |
| coiled_coil | n/a | 805 | 825 |
| disorder | n/a | 809 | 810 |
| disorder | n/a | 862 | 869 |
| disorder | n/a | 871 | 874 |
| disorder | n/a | 876 | 879 |
| Pfam A | Microtub_bind | 916 | 1054 |
| disorder | n/a | 924 | 926 |
| disorder | n/a | 930 | 936 |
| disorder | n/a | 944 | 947 |
| disorder | n/a | 949 | 952 |
| disorder | n/a | 959 | 966 |
| disorder | n/a | 969 | 971 |
| disorder | n/a | 973 | 981 |
| disorder | n/a | 983 | 991 |
| disorder | n/a | 993 | 999 |
| disorder | n/a | 1013 | 1044 |
| disorder | n/a | 1046 | 1047 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P52732. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MASQPNSSAK KKEEKGKNIQ VVVRCRPFNL AERKASAHSI VECDPVRKEV
50 51
SVRTGGLADK SSRKTYTFDM VFGASTKQID VYRSVVCPIL DEVIMGYNCT
100 101
IFAYGQTGTG KTFTMEGERS PNEEYTWEED PLAGIIPRTL HQIFEKLTDN
150 151
GTEFSVKVSL LEIYNEELFD LLNPSSDVSE RLQMFDDPRN KRGVIIKGLE
200 201
EITVHNKDEV YQILEKGAAK RTTAATLMNA YSSRSHSVFS VTIHMKETTI
250 251
DGEELVKIGK LNLVDLAGSE NIGRSGAVDK RAREAGNINQ SLLTLGRVIT
300 301
ALVERTPHVP YRESKLTRIL QDSLGGRTRT SIIATISPAS LNLEETLSTL
350 351
EYAHRAKNIL NKPEVNQKLT KKALIKEYTE EIERLKRDLA AAREKNGVYI
400 401
SEENFRVMSG KLTVQEEQIV ELIEKIGAVE EELNRVTELF MDNKNELDQC
450 451
KSDLQNKTQE LETTQKHLQE TKLQLVKEEY ITSALESTEE KLHDAASKLL
500 501
NTVEETTKDV SGLHSKLDRK KAVDQHNAEA QDIFGKNLNS LFNNMEELIK
550 551
DGSSKQKAML EVHKTLFGNL LSSSVSALDT ITTVALGSLT SIPENVSTHV
600 601
SQIFNMILKE QSLAAESKTV LQELINVLKT DLLSSLEMIL SPTVVSILKI
650 651
NSQLKHIFKT SLTVADKIED QKKELDGFLS ILCNNLHELQ ENTICSLVES
700 701
QKQCGNLTED LKTIKQTHSQ ELCKLMNLWT ERFCALEEKC ENIQKPLSSV
750 751
QENIQQKSKD IVNKMTFHSQ KFCADSDGFS QELRNFNQEG TKLVEESVKH
800 801
SDKLNGNLEK ISQETEQRCE SLNTRTVYFS EQWVSSLNER EQELHNLLEV
850 851
VSQCCEASSS DITEKSDGRK AAHEKQHNIF LDQMTIDEDK LIAQNLELNE
900 901
TIKIGLTKLN CFLEQDLKLD IPTGTTPQRK SYLYPSTLVR TEPREHLLDQ
950 951
LKRKQPELLM MLNCSENNKE ETIPDVDVEE AVLGQYTEEP LSQEPSVDAG
1000 1001
VDCSSIGGVP FFQHKKSHGK DKENRGINTL ERSKVEETTE HLVTKSRLPL
1050 1051
RAQINL
1056
Show the unformatted sequence. |
| Checksums: |
CRC64:C7F2606FE68DA8EA
MD5:4ab6e18b288f8eac32adff73b55d3254
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.