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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PTN5_HUMAN (P54829)

Summary

This is the summary of UniProt entry PTN5_HUMAN (P54829).

Description: Tyrosine-protein phosphatase non-receptor type 5 EC=3.1.3.48
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 565 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 22
disorder n/a 24 27
disorder n/a 37 78
low_complexity n/a 57 74
transmembrane n/a 88 111
low_complexity n/a 119 130
low_complexity n/a 143 182
transmembrane n/a 145 166
disorder n/a 168 184
disorder n/a 219 220
disorder n/a 231 237
disorder n/a 250 251
disorder n/a 265 266
Pfam A Y_phosphatase 323 553

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P54829. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNYEGARSER ENHAADDSEG GALDMCCSER LPGLPQPIVM EALDEAEGLQ
50
51
DSQREMPPPP PPSPPSDPAQ KPPPRGAGSH SLTVRSSLCL FAASQFLLAC
100
101
GVLWFSGYGH IWSQNATNLV SSLLTLLKQL EPTAWLDSGT WGVPSLLLVF
150
151
LSVGLVLVTT LVWHLLRTPP EPPTPLPPED RRQSVSRQPS FTYSEWMEEK
200
201
IEDDFLDLDP VPETPVFDCV MDIKPEADPT SLTVKSMGLQ ERRGSNVSLT
250
251
LDMCTPGCNE EGFGYLMSPR EESAREYLLS ASRVLQAEEL HEKALDPFLL
300
301
QAEFFEIPMN FVDPKEYDIP GLVRKNRYKT ILPNPHSRVC LTSPDPDDPL
350
351
SSYINANYIR GYGGEEKVYI ATQGPIVSTV ADFWRMVWQE HTPIIVMITN
400
401
IEEMNEKCTE YWPEEQVAYD GVEITVQKVI HTEDYRLRLI SLKSGTEERG
450
451
LKHYWFTSWP DQKTPDRAPP LLHLVREVEE AAQQEGPHCA PIIVHCSAGI
500
501
GRTGCFIATS ICCQQLRQEG VVDILKTTCQ LRQDRGGMIQ TCEQYQFVHH
550
551
VMSLYEKQLS HQSPE                                      
565
 

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Checksums:
CRC64:DE32BEFFEFF7C494
MD5:b33ad732dc5c57aa912b6dc5359df447

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Y_phosphatase 323 - 553 2BIJ A 299 - 529 Jmol AstexViewer SPICE
2BV5 A 299 - 529 Jmol AstexViewer SPICE
2CJZ A 299 - 529 Jmol AstexViewer SPICE