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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RAD_HUMAN (P55042)

Summary

This is the summary of UniProt entry RAD_HUMAN (P55042).

Description: GTP-binding protein RAD
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 308 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 85
low_complexity n/a 5 26
low_complexity n/a 48 68
low_complexity n/a 74 90
Pfam A Ras 93 253
disorder n/a 113 115
disorder n/a 118 119
disorder n/a 122 128
disorder n/a 258 270

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P55042. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTLNGGGSGA GGSRGGGQER ERRRGSTPWG PAPPLHRRSM PVDERDLQAA
50
51
LTPGALTAAA AGTGTQGPRL DWPEDSEDSL SSGGSDSDES VYKVLLLGAP
100
101
GVGKSALARI FGGVEDGPEA EAAGHTYDRS IVVDGEEASL MVYDIWEQDG
150
151
GRWLPGHCMA MGDAYVIVYS VTDKGSFEKA SELRVQLRRA RQTDDVPIIL
200
201
VGNKSDLVRS REVSVDEGRA CAVVFDCKFI ETSAALHHNV QALFEGVVRQ
250
251
IRLRRDSKEA NARRQAGTRR RESLGKKAKR FLGRIVARNS RKMAFRAKSK
300
301
SCHDLSVL                                              
308
 

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Checksums:
CRC64:EF098960A371D2C4
MD5:e83c86bda32c0fd97064af1a74be4f41

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ras 93 - 253 2DPX A 93 - 253 Jmol AstexViewer SPICE
B 93 - 253 Jmol AstexViewer SPICE
2GJS A 93 - 253 Jmol AstexViewer SPICE
B 93 - 253 Jmol AstexViewer SPICE
3Q72 A 93 - 253 Jmol AstexViewer SPICE
B 93 - 253 Jmol AstexViewer SPICE
3Q7P A 93 - 253 Jmol AstexViewer SPICE
B 93 - 253 Jmol AstexViewer SPICE
3Q7Q A 93 - 253 Jmol AstexViewer SPICE
B 93 - 253 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.