Summary
This is the summary of UniProt entry CADH8_HUMAN (P55286).
| Description: | Cadherin-8 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 799 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| low_complexity | n/a | 9 | 25 |
| transmembrane | n/a | 12 | 30 |
| Pfam A | Cadherin | 67 | 158 |
| disorder | n/a | 167 | 169 |
| Pfam A | Cadherin | 172 | 267 |
| disorder | n/a | 186 | 187 |
| disorder | n/a | 227 | 229 |
| low_complexity | n/a | 250 | 267 |
| disorder | n/a | 260 | 264 |
| disorder | n/a | 267 | 268 |
| Pfam A | Cadherin | 281 | 383 |
| disorder | n/a | 301 | 303 |
| disorder | n/a | 309 | 311 |
| Pfam A | Cadherin | 396 | 487 |
| Pfam A | Cadherin | 500 | 597 |
| disorder | n/a | 514 | 519 |
| transmembrane | n/a | 613 | 642 |
| low_complexity | n/a | 623 | 640 |
| Pfam A | Cadherin_C | 645 | 793 |
| disorder | n/a | 664 | 668 |
| low_complexity | n/a | 668 | 676 |
| disorder | n/a | 676 | 682 |
| disorder | n/a | 729 | 732 |
| disorder | n/a | 735 | 747 |
| disorder | n/a | 757 | 764 |
| low_complexity | n/a | 758 | 770 |
| disorder | n/a | 766 | 767 |
| disorder | n/a | 770 | 771 |
| disorder | n/a | 794 | 799 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P55286. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MPERLAEMLL DLWTPLIILW ITLPPCIYMA PMNQSQVLMS GSPLELNSLG
50 51
EEQRILNRSK RGWVWNQMFV LEEFSGPEPI LVGRLHTDLD PGSKKIKYIL
100 101
SGDGAGTIFQ INDVTGDIHA IKRLDREEKA EYTLTAQAVD WETSKPLEPP
150 151
SEFIIKVQDI NDNAPEFLNG PYHATVPEMS ILGTSVTNVT ATDADDPVYG
200 201
NSAKLVYSIL EGQPYFSIEP ETAIIKTALP NMDREAKEEY LVVIQAKDMG
250 251
GHSGGLSGTT TLTVTLTDVN DNPPKFAQSL YHFSVPEDVV LGTAIGRVKA
300 301
NDQDIGENAQ SSYDIIDGDG TALFEITSDA QAQDGIIRLR KPLDFETKKS
350 351
YTLKVEAANV HIDPRFSGRG PFKDTATVKI VVEDADEPPV FSSPTYLLEV
400 401
HENAALNSVI GQVTARDPDI TSSPIRFSID RHTDLERQFN INADDGKITL
450 451
ATPLDRELSV WHNITIIATE IRNHSQISRV PVAIKVLDVN DNAPEFASEY
500 501
EAFLCENGKP GQVIQTVSAM DKDDPKNGHY FLYSLLPEMV NNPNFTIKKN
550 551
EDNSLSILAK HNGFNRQKQE VYLLPIIISD SGNPPLSSTS TLTIRVCGCS
600 601
NDGVVQSCNV EAYVLPIGLS MGALIAILAC IILLLVIVVL FVTLRRHKNE
650 651
PLIIKDDEDV RENIIRYDDE GGGEEDTEAF DIATLQNPDG INGFLPRKDI
700 701
KPDLQFMPRQ GLAPVPNGVD VDEFINVRLH EADNDPTAPP YDSIQIYGYE
750 751
GRGSVAGSLS SLESTTSDSD QNFDYLSDWG PRFKRLGELY SVGESDKET
799
Show the unformatted sequence. |
| Checksums: |
CRC64:9B119B86039C6A0A
MD5:00e0e3f4f4900ba01973243043124a21
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.