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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: DNLI_PYRFU (P56709)

Summary

This is the summary of UniProt entry DNLI_PYRFU (P56709).

Description: DNA ligase EC=6.5.1.1
Source organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (NCBI taxonomy ID 186497)
View Pfam proteome data.
Length: 561 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A DNA_ligase_A_N 1 177
low_complexity n/a 99 109
Pfam A DNA_ligase_A_M 224 422
Pfam A DNA_ligase_A_C 442 534

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P56709. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRYLELAQLY QKLEKTTMKL IKTRLVADFL KKVPDDHLEF IPYLILGEVF
50
51
PEWDERELGV GEKLLIKAVA MATGIDAKEI EESVKDTGDL GESIALAVKK
100
101
KKQKSFFSQP LTIKRVYQTL VKVAETTGEG SQDKKVKYLA DLFMDAEPLE
150
151
AKYLARTILG TMRTGVAEGL LRDAIAMAFH VKVELVERAY MLTSDFGYVA
200
201
KIAKLEGNEG LAKVQVQLGK PIKPMLAQQA ASIRDALLEM GGEAEFEIKY
250
251
DGARVQVHKD GSKIIVYSRR LENVTRAIPE IVEALKEAII PEKAIVEGEL
300
301
VAIGENGRPL PFQYVLRRFR RKHNIEEMME KIPLELNLFD VLYVDGQSLI
350
351
DTKFIDRRRT LEEIIKQNEK IKVAENLITK KVEEAEAFYK RALEMGHEGL
400
401
MAKRLDAVYE PGNRGKKWLK IKPTMENLDL VIIGAEWGEG RRAHLFGSFI
450
451
LGAYDPETGE FLEVGKVGSG FTDDDLVEFT KMLKPLIIKE EGKRVWLQPK
500
501
VVIEVTYQEI QKSPKYRSGF ALRFPRFVAL RDDKGPEDAD TIERIAQLYE
550
551
LQEKMKGKVE S                                          
561
 

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Checksums:
CRC64:534158525B9D24B2
MD5:f4896ca3068541867d60226a0632b213

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
DNA_ligase_A_C 442 - 534 2CFM A 442 - 534 Jmol AstexViewer SPICE
DNA_ligase_A_M 224 - 422 2CFM A 224 - 422 Jmol AstexViewer SPICE
DNA_ligase_A_N 1 - 177 2CFM A 1 - 177 Jmol AstexViewer SPICE