Summary
This is the summary of UniProt entry NANA_STRR6 (P62576).
| Description: | Sialidase A EC=3.2.1.18 |
| Source organism: |
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
(NCBI taxonomy ID
171101)
View Pfam proteome data. |
| Length: | 1035 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 4 | 17 |
| Pfam A | YSIRK_signal | 21 | 47 |
| transmembrane | n/a | 32 | 53 |
| disorder | n/a | 52 | 110 |
| low_complexity | n/a | 93 | 105 |
| Pfam A | Sialidase | 118 | 309 |
| disorder | n/a | 121 | 144 |
| low_complexity | n/a | 138 | 150 |
| disorder | n/a | 150 | 152 |
| disorder | n/a | 154 | 155 |
| disorder | n/a | 199 | 201 |
| disorder | n/a | 206 | 208 |
| disorder | n/a | 226 | 227 |
| disorder | n/a | 303 | 305 |
| disorder | n/a | 307 | 310 |
| Pfam B | Pfam-B_916 | 311 | 490 |
| disorder | n/a | 324 | 336 |
| disorder | n/a | 341 | 345 |
| disorder | n/a | 391 | 408 |
| disorder | n/a | 411 | 417 |
| disorder | n/a | 476 | 479 |
| disorder | n/a | 601 | 603 |
| Pfam A | BNR | 607 | 618 |
| disorder | n/a | 618 | 649 |
| disorder | n/a | 712 | 714 |
| disorder | n/a | 723 | 727 |
| disorder | n/a | 799 | 800 |
| Pfam B | Pfam-B_1411 | 817 | 900 |
| disorder | n/a | 859 | 867 |
| disorder | n/a | 874 | 982 |
| Pfam B | Pfam-B_1411 | 956 | 1024 |
| disorder | n/a | 988 | 991 |
| disorder | n/a | 994 | 1011 |
| transmembrane | n/a | 1013 | 1030 |
| low_complexity | n/a | 1013 | 1030 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P62576. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSYFRNRDID IERNSMNRSV QERKCRYSIR KLSVGAVSMI VGAVVFGTSP
50 51
VLAQEGASEQ PLANETQLSG ESSTLTDTEK SQPSSETELS GNKQEQERKD
100 101
KQEEKIPRDY YARDLENVET VIEKEDVETN ASNGQRVDLS SELDKLKKLE
150 151
NATVHMEFKP DAKAPAFYNL FSVSSATKKD EYFTMAVYNN TATLEGRGSD
200 201
GKQFYNNYND APLKVKPGQW NSVTFTVEKP TAELPKGRVR LYVNGVLSRT
250 251
SLRSGNFIKD MPDVTHVQIG ATKRANNTVW GSNLQIRNLT VYNRALTPEE
300 301
VQKRSQLFKR SDLEKKLPEG AALTEKTDIF ESGRNGKPNK DGIKSYRIPA
350 351
LLKTDKGTLI AGADERRLHS SDWGDIGMVI RRSEDNGKTW GDRVTITNLR
400 401
DNPKASDPSI GSPVNIDMVL VQDPETKRIF SIYDMFPEGK GIFGMSSQKE
450 451
EAYKKIDGKT YQILYREGEK GAYTIRENGT VYTPDGKATD YRVVVDPVKP
500 501
AYSDKGDLYK GNQLLGNIYF TTNKTSPFRI AKDSYLWMSY SDDDGKTWSA
550 551
PQDITPMVKA DWMKFLGVGP GTGIVLRNGP HKGRILIPVY TTNNVSHLNG
600 601
SQSSRIIYSD DHGKTWHAGE AVNDNRQVDG QKIHSSTMNN RRAQNTESTV
650 651
VQLNNGDVKL FMRGLTGDLQ VATSKDGGVT WEKDIKRYPQ VKDVYVQMSA
700 701
IHTMHEGKEY IILSNAGGPK RENGMVHLAR VEENGELTWL KHNPIQKGEF
750 751
AYNSLQELGN GEYGILYEHT EKGQNAYTLS FRKFNWDFLS KDLISPTEAK
800 801
VKRTREMGKG VIGLEFDSEV LVNKAPTLQL ANGKTARFMT QYDTKTLLFT
850 851
VDSEDMGQKV TGLAEGAIES MHNLPVSVAG TKLSNGMNGS EAAVHEVPEY
900 901
TGPLGTSGEE PAPTVEKPEY TGPLGTSGEE PAPTVEKPEY TGPLGTAGEE
950 951
AAPTVEKPEF TGGVNGTEPA VHEIAEYKGS DSLVTLTTKE DYTYKAPLAQ
1000 1001
QALPETGNKE SDLLASLGLT AFFLGLFTLG KKREQ
1035
Show the unformatted sequence. |
| Checksums: |
CRC64:C5B8A2D7A12E12F3
MD5:10866d349b6fca837fe416f0101f863b
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| BNR | 607 - 618 | 2W20 | A | 607 - 618 | Jmol AstexViewer SPICE |
| B | 607 - 618 | Jmol AstexViewer SPICE | |||
| 3H71 | A | 607 - 618 | Jmol AstexViewer SPICE | ||
| B | 607 - 618 | Jmol AstexViewer SPICE | |||
| 3H72 | A | 607 - 618 | Jmol AstexViewer SPICE | ||
| B | 607 - 618 | Jmol AstexViewer SPICE | |||
| 3H73 | A | 607 - 618 | Jmol AstexViewer SPICE | ||
| B | 607 - 618 | Jmol AstexViewer SPICE |