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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CANB1_HUMAN (P63098)

Summary

This is the summary of UniProt entry CANB1_HUMAN (P63098).

Description: Calcineurin subunit B type 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 170 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A EF-hand_7 19 79
Pfam A EF-hand_5 23 47
Pfam A EF-hand_1 91 119
Pfam A EF-hand_7 91 157

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P63098. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGNEASYPLE MCSHFDADEI KRLGKRFKKL DLDNSGSLSV EEFMSLPELQ
50
51
QNPLVQRVID IFDTDGNGEV DFKEFIEGVS QFSVKGDKEQ KLRFAFRIYD
100
101
MDKDGYISNG ELFQVLKMMV GNNLKDTQLQ QIVDKTIINA DKDGDGRISF
150
151
EEFCAVVGGL DIHKKMVVDV                                 
170
 

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Checksums:
CRC64:C904715DC0386056
MD5:ec30ec4498d46848a5d56197a61bee82

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EF-hand_1 91 - 119 1AUI B 90 - 118 Jmol AstexViewer SPICE
1M63 B 90 - 118 Jmol AstexViewer SPICE
F 90 - 118 Jmol AstexViewer SPICE
1MF8 B 90 - 118 Jmol AstexViewer SPICE
2P6B B 90 - 118 Jmol AstexViewer SPICE
D 90 - 118 Jmol AstexViewer SPICE
3LL8 B 90 - 118 Jmol AstexViewer SPICE
D 90 - 118 Jmol AstexViewer SPICE
EF-hand_5 23 - 47 1AUI B 22 - 46 Jmol AstexViewer SPICE
1M63 B 22 - 46 Jmol AstexViewer SPICE
F 22 - 46 Jmol AstexViewer SPICE
1MF8 B 22 - 46 Jmol AstexViewer SPICE
2P6B B 22 - 46 Jmol AstexViewer SPICE
D 22 - 46 Jmol AstexViewer SPICE
3LL8 B 22 - 46 Jmol AstexViewer SPICE
D 22 - 46 Jmol AstexViewer SPICE
EF-hand_7 19 - 79 1AUI B 18 - 78 Jmol AstexViewer SPICE
1M63 B 18 - 78 Jmol AstexViewer SPICE
F 18 - 78 Jmol AstexViewer SPICE
1MF8 B 18 - 78 Jmol AstexViewer SPICE
2P6B B 18 - 78 Jmol AstexViewer SPICE
D 18 - 78 Jmol AstexViewer SPICE
3LL8 B 18 - 78 Jmol AstexViewer SPICE
D 18 - 78 Jmol AstexViewer SPICE
91 - 157 1AUI B 90 - 156 Jmol AstexViewer SPICE
1M63 B 90 - 156 Jmol AstexViewer SPICE
F 90 - 156 Jmol AstexViewer SPICE
1MF8 B 90 - 156 Jmol AstexViewer SPICE
2P6B B 90 - 156 Jmol AstexViewer SPICE
D 90 - 156 Jmol AstexViewer SPICE
3LL8 B 90 - 156 Jmol AstexViewer SPICE
D 90 - 156 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.