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27  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PGH2_MOUSE (Q05769)

Summary

This is the summary of UniProt entry PGH2_MOUSE (Q05769).

Description: Prostaglandin G/H synthase 2 EC=1.14.99.1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 604 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 17
Pfam A An_peroxidase 125 208
disorder n/a 149 152
low_complexity n/a 182 198
Pfam A An_peroxidase 204 568
disorder n/a 574 583

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q05769. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLFRAVLLCA ALGLSQAANP CCSNPCQNRG ECMSTGFDQY KCDCTRTGFY
50
51
GENCTTPEFL TRIKLLLKPT PNTVHYILTH FKGVWNIVNN IPFLRSLIMK
100
101
YVLTSRSYLI DSPPTYNVHY GYKSWEAFSN LSYYTRALPP VADDCPTPMG
150
151
VKGNKELPDS KEVLEKVLLR REFIPDPQGS NMMFAFFAQH FTHQFFKTDH
200
201
KRGPGFTRGL GHGVDLNHIY GETLDRQHKL RLFKDGKLKY QVIGGEVYPP
250
251
TVKDTQVEMI YPPHIPENLQ FAVGQEVFGL VPGLMMYATI WLREHNRVCD
300
301
ILKQEHPEWG DEQLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE
350
351
LLFNQQFQYQ NRIASEFNTL YHWHPLLPDT FNIEDQEYSF KQFLYNNSIL
400
401
LEHGLTQFVE SFTRQIAGRV AGGRNVPIAV QAVAKASIDQ SREMKYQSLN
450
451
EYRKRFSLKP YTSFEELTGE KEMAAELKAL YSDIDVMELY PALLVEKPRP
500
501
DAIFGETMVE LGAPFSLKGL MGNPICSPQY WKPSTFGGEV GFKIINTASI
550
551
QSLICNNVKG CPFTSFNVQD PQPTKTATIN ASASHSRLDD INPTVLIKRR
600
601
STEL                                                  
604
 

Show the unformatted sequence.

Checksums:
CRC64:DFE1658295C92064
MD5:4d748dc1f81ad7bfea845b17bf2bed77

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
An_peroxidase 125 - 208 1CVU A 139 - 222 Jmol AstexViewer SPICE
B 2139 - 2222 Jmol AstexViewer SPICE
1CX2 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
C 139 - 222 Jmol AstexViewer SPICE
D 139 - 222 Jmol AstexViewer SPICE
1DDX A 139 - 222 Jmol AstexViewer SPICE
B 1139 - 1222 Jmol AstexViewer SPICE
C 2139 - 2222 Jmol AstexViewer SPICE
D 3139 - 3222 Jmol AstexViewer SPICE
1PXX A 139 - 222 Jmol AstexViewer SPICE
B 1139 - 1222 Jmol AstexViewer SPICE
C 2139 - 2222 Jmol AstexViewer SPICE
D 3139 - 3222 Jmol AstexViewer SPICE
3HS5 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3HS6 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3HS7 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3KRK A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3LN0 A 125 - 208 Jmol AstexViewer SPICE
B 125 - 208 Jmol AstexViewer SPICE
C 125 - 208 Jmol AstexViewer SPICE
D 125 - 208 Jmol AstexViewer SPICE
3LN1 A 125 - 208 Jmol AstexViewer SPICE
B 125 - 208 Jmol AstexViewer SPICE
C 125 - 208 Jmol AstexViewer SPICE
D 125 - 208 Jmol AstexViewer SPICE
3MDL A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3MQE A 125 - 208 Jmol AstexViewer SPICE
B 125 - 208 Jmol AstexViewer SPICE
C 125 - 208 Jmol AstexViewer SPICE
D 125 - 208 Jmol AstexViewer SPICE
3NT1 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3NTB A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
C 139 - 222 Jmol AstexViewer SPICE
D 139 - 222 Jmol AstexViewer SPICE
3NTG A 125 - 208 Jmol AstexViewer SPICE
B 125 - 208 Jmol AstexViewer SPICE
C 125 - 208 Jmol AstexViewer SPICE
D 125 - 208 Jmol AstexViewer SPICE
3OLT A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3OLU A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3PGH A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
C 139 - 222 Jmol AstexViewer SPICE
D 139 - 222 Jmol AstexViewer SPICE
3Q7D A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3QH0 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3QMO A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
3RR3 A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
C 139 - 222 Jmol AstexViewer SPICE
D 139 - 222 Jmol AstexViewer SPICE
3TZI A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
4COX A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
C 139 - 222 Jmol AstexViewer SPICE
D 139 - 222 Jmol AstexViewer SPICE
4E1G A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
5COX A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
C 139 - 222 Jmol AstexViewer SPICE
D 139 - 222 Jmol AstexViewer SPICE
6COX A 139 - 222 Jmol AstexViewer SPICE
B 139 - 222 Jmol AstexViewer SPICE
204 - 568 1CVU A 218 - 582 Jmol AstexViewer SPICE
B 2218 - 2582 Jmol AstexViewer SPICE
1CX2 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
C 218 - 582 Jmol AstexViewer SPICE
D 218 - 582 Jmol AstexViewer SPICE
1DDX A 218 - 582 Jmol AstexViewer SPICE
B 1218 - 1582 Jmol AstexViewer SPICE
C 2218 - 2582 Jmol AstexViewer SPICE
D 3218 - 3582 Jmol AstexViewer SPICE
1PXX A 218 - 582 Jmol AstexViewer SPICE
B 1218 - 1582 Jmol AstexViewer SPICE
C 2218 - 2582 Jmol AstexViewer SPICE
D 3218 - 3582 Jmol AstexViewer SPICE
3HS5 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3HS6 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3HS7 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3KRK A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3LN0 A 204 - 568 Jmol AstexViewer SPICE
B 204 - 568 Jmol AstexViewer SPICE
C 204 - 568 Jmol AstexViewer SPICE
D 204 - 568 Jmol AstexViewer SPICE
3LN1 A 204 - 568 Jmol AstexViewer SPICE
B 204 - 568 Jmol AstexViewer SPICE
C 204 - 568 Jmol AstexViewer SPICE
D 204 - 568 Jmol AstexViewer SPICE
3MDL A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3MQE A 204 - 568 Jmol AstexViewer SPICE
B 204 - 568 Jmol AstexViewer SPICE
C 204 - 568 Jmol AstexViewer SPICE
D 204 - 568 Jmol AstexViewer SPICE
3NT1 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3NTB A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
C 218 - 582 Jmol AstexViewer SPICE
D 218 - 582 Jmol AstexViewer SPICE
3NTG A 204 - 568 Jmol AstexViewer SPICE
B 204 - 568 Jmol AstexViewer SPICE
C 204 - 568 Jmol AstexViewer SPICE
D 204 - 568 Jmol AstexViewer SPICE
3OLT A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3OLU A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3PGH A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
C 218 - 582 Jmol AstexViewer SPICE
D 218 - 582 Jmol AstexViewer SPICE
3Q7D A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3QH0 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3QMO A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
3RR3 A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
C 218 - 582 Jmol AstexViewer SPICE
D 218 - 582 Jmol AstexViewer SPICE
3TZI A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
4COX A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
C 218 - 582 Jmol AstexViewer SPICE
D 218 - 582 Jmol AstexViewer SPICE
4E1G A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
5COX A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE
C 218 - 582 Jmol AstexViewer SPICE
D 218 - 582 Jmol AstexViewer SPICE
6COX A 218 - 582 Jmol AstexViewer SPICE
B 218 - 582 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.