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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PTN11_HUMAN (Q06124)

Summary

This is the summary of UniProt entry PTN11_HUMAN (Q06124).

Description: Tyrosine-protein phosphatase non-receptor type 11 EC=3.1.3.48
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 597 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A SH2 6 81
disorder n/a 41 42
Pfam A SH2 112 197
disorder n/a 133 135
disorder n/a 147 155
disorder n/a 158 165
disorder n/a 208 209
disorder n/a 223 224
disorder n/a 265 267
Pfam A Y_phosphatase 273 524
disorder n/a 273 279
disorder n/a 296 297
low_complexity n/a 474 483
disorder n/a 532 534
disorder n/a 536 541
disorder n/a 544 546
disorder n/a 549 552
disorder n/a 554 555
disorder n/a 557 581
low_complexity n/a 563 573

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q06124. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTSRRWFHPN ITGVEAENLL LTRGVDGSFL ARPSKSNPGD FTLSVRRNGA
50
51
VTHIKIQNTG DYYDLYGGEK FATLAELVQY YMEHHGQLKE KNGDVIELKY
100
101
PLNCADPTSE RWFHGHLSGK EAEKLLTEKG KHGSFLVRES QSHPGDFVLS
150
151
VRTGDDKGES NDGKSKVTHV MIRCQELKYD VGGGERFDSL TDLVEHYKKN
200
201
PMVETLGTVL QLKQPLNTTR INAAEIESRV RELSKLAETT DKVKQGFWEE
250
251
FETLQQQECK LLYSRKEGQR QENKNKNRYK NILPFDHTRV VLHDGDPNEP
300
301
VSDYINANII MPEFETKCNN SKPKKSYIAT QGCLQNTVND FWRMVFQENS
350
351
RVIVMTTKEV ERGKSKCVKY WPDEYALKEY GVMRVRNVKE SAAHDYTLRE
400
401
LKLSKVGQAL LQGNTERTVW QYHFRTWPDH GVPSDPGGVL DFLEEVHHKQ
450
451
ESIMDAGPVV VHCSAGIGRT GTFIVIDILI DIIREKGVDC DIDVPKTIQM
500
501
VRSQRSGMVQ TEAQYRFIYM AVQHYIETLQ RRIEEEQKSK RKGHEYTNIK
550
551
YSLADQTSGD QSPLPPCTPT PPCAEMREDS ARVYENVGLM QQQKSFR   
597
 

Show the unformatted sequence.

Checksums:
CRC64:37E8BFC7ECA2D03F
MD5:4d74727016f5ab7a62c67fda09a05c3d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SH2 112 - 197 2SHP A 112 - 197 Jmol AstexViewer SPICE
B 112 - 197 Jmol AstexViewer SPICE
6 - 81 2SHP A 6 - 81 Jmol AstexViewer SPICE
B 6 - 81 Jmol AstexViewer SPICE
3TKZ A 6 - 81 Jmol AstexViewer SPICE
3TL0 A 6 - 81 Jmol AstexViewer SPICE
Y_phosphatase 273 - 524 2SHP A 273 - 520 Jmol AstexViewer SPICE
B 273 - 520 Jmol AstexViewer SPICE
3B7O A 273 - 520 Jmol AstexViewer SPICE
3MOW A 273 - 520 Jmol AstexViewer SPICE
3O5X A 273 - 520 Jmol AstexViewer SPICE