Summary
This is the summary of UniProt entry NRAM_I63A3 (Q07599).
| Description: | Neuraminidase EC=3.2.1.18 |
| Source organism: |
Influenza A virus (strain A/Duck/Ukraine/1/1963 H3N8)
(NCBI taxonomy ID
385580)
|
| Length: | 470 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Neur | 1 | 465 |
| transmembrane | n/a | 12 | 36 |
| disorder | n/a | 327 | 334 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q07599. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MNPNQKIITI GSISLGLVVF NVLLHVVSII VTVLVLGKGG NNGICNETVV
50 51
REYNETVRIE KVTQWHNTNV VEYVPYWNGG TYMNNTEAIC DAKGFAPFSK
100 101
DNGIRIGSRG HIFVIREPFV SCSPIECRTF FLTQGSLLND KHSNGTVKDR
150 151
SPFRTLMSVE VGQSPNVYQA RFEAVAWSAT ACHDGKKWMT VGVTGPDSKA
200 201
VAVIHYGGVP TDVVNSWAGD ILRTQESSCT CIQGDCYWVM TDGPANRQAQ
250 251
YRIYKANQGR IIGQTDISFN GGHIEECSCY PNDGKVECVC RDGWTGTNRP
300 301
VLVISPDLSY RVGYLCAGIP SDTPRGEDTQ FTGSCTSPMG NQGYGVKGFG
350 351
FRQGTDVWMG RTISRTSRSG FEILRIKNGW TQTSKEQIRK QVVVDNLNWS
400 401
GYSGSFTLPV ELSGKDCLVP CFWVEMIRGK PEEKTIWTSS SSIVMCGVDY
450 451
EVADWSWHDG AILPFDIDKM
470
Show the unformatted sequence. |
| Checksums: |
CRC64:B46D54A03AC84CCE
MD5:cb2ebcd38a9b7485bc2f53634af65639
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Neur | 81 - 465 | 2HT5 | A | 83 - 466 | Jmol AstexViewer SPICE |
| 2HT7 | A | 83 - 466 | Jmol AstexViewer SPICE | ||
| 2HT8 | A | 83 - 466 | Jmol AstexViewer SPICE | ||
| 2HTQ | A | 83 - 466 | Jmol AstexViewer SPICE | ||
| 2HTR | A | 83 - 466 | Jmol AstexViewer SPICE | ||
| 2HTU | A | 83 - 476 | Jmol AstexViewer SPICE | ||
| 3O9J | A | 83 - 476 | Jmol AstexViewer SPICE | ||
| 3O9K | A | 83 - 476 | Jmol AstexViewer SPICE |