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15  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ACE_DROME (Q10714)

Summary

This is the summary of UniProt entry ACE_DROME (Q10714).

Description: Angiotensin-converting enzyme EC=3.4.15.1
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
View Pfam proteome data.
Length: 615 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 3 19
Pfam A Peptidase_M2 11 612
coiled_coil n/a 18 45

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q10714. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRLFLLALLA TLAVTQALVK EEIQAKEYLE NLNKELAKRT NVETEAAWAY
50
51
GSNITDENEK KKNEISAELA KFMKEVASDT TKFQWRSYQS EDLKRQFKAL
100
101
TKLGYAALPE DDYAELLDTL SAMESNFAKV KVCDYKDSTK CDLALDPEIE
150
151
EVISKSRDHE ELAYYWREFY DKAGTAVRSQ FERYVELNTK AAKLNNFTSG
200
201
AEAWLDEYED DTFEQQLEDI FADIRPLYQQ IHGYVRFRLR KHYGDAVVSE
250
251
TGPIPMHLLG NMWAQQWSEI ADIVSPFPEK PLVDVSAEME KQGYTPLKMF
300
301
QMGDDFFTSM NLTKLPQDFW DKSIIEKPTD GRDLVCHASA WDFYLTDDVR
350
351
IKQCTRVTQD QLFTVHHELG HIQYFLQYQH QPFVYRTGAN PGFHEAVGDV
400
401
LSLSVSTPKH LEKIGLLKDY VRDDEARINQ LFLTALDKIV FLPFAFTMDK
450
451
YRWSLFRGEV DKANWNCAFW KLRDEYSGIE PPVVRSEKDF DAPAKYHISA
500
501
DVEYLRYLVS FIIQFQFYKS ACIKAGQYDP DNVELPLDNC DIYGSAAAGA
550
551
AFHNMLSMGA SKPWPDALEA FNGERIMSGK AIAEYFEPLR VWLEAENIKN
600
601
NVHIGWTTSN KCVSS                                      
615
 

Show the unformatted sequence.

Checksums:
CRC64:9E3691BCC51D6C48
MD5:e7dd87cb552e135e9d6841e52a261d30

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Peptidase_M2 17 - 612 2X8Z A 17 - 612 Jmol AstexViewer SPICE
2X90 A 17 - 612 Jmol AstexViewer SPICE
2X92 A 17 - 612 Jmol AstexViewer SPICE
2X93 A 17 - 612 Jmol AstexViewer SPICE
2X94 A 17 - 612 Jmol AstexViewer SPICE
2X95 A 17 - 612 Jmol AstexViewer SPICE
2X96 A 17 - 612 Jmol AstexViewer SPICE
2X97 A 17 - 612 Jmol AstexViewer SPICE
2XHM A 17 - 612 Jmol AstexViewer SPICE
19 - 612 3ZQZ A 19 - 612 Jmol AstexViewer SPICE
20 - 612 2X8Y A 20 - 612 Jmol AstexViewer SPICE
2X91 A 20 - 612 Jmol AstexViewer SPICE
23 - 612 1J36 A 23 - 612 Jmol AstexViewer SPICE
B 23 - 612 Jmol AstexViewer SPICE
1J37 A 23 - 612 Jmol AstexViewer SPICE
B 23 - 612 Jmol AstexViewer SPICE
1J38 A 23 - 612 Jmol AstexViewer SPICE
B 23 - 612 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.