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48  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PIN1_HUMAN (Q13526)

Summary

This is the summary of UniProt entry PIN1_HUMAN (Q13526).

Description: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 EC=5.2.1.8
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 163 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 13
Pfam A WW 7 37
disorder n/a 34 61
low_complexity n/a 38 48
Pfam A Rotamase 59 163
disorder n/a 68 80
disorder n/a 121 122
disorder n/a 124 127
disorder n/a 136 139

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q13526. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MADEEKLPPG WEKRMSRSSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG
50
51
EPARVRCSHL LVKHSQSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE
100
101
EDFESLASQF SDCSSAKARG DLGAFSRGQM QKPFEDASFA LRTGEMSGPV
150
151
FTDSGIHIIL RTE                                        
163
 

Show the unformatted sequence.

Checksums:
CRC64:35391AF40B7D1E13
MD5:bae5efdfc0671b321fa8118b872a5e3d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Rotamase 59 - 161 1ZCN A 59 - 161 Jmol AstexViewer SPICE
59 - 162 2F21 A 59 - 162 Jmol AstexViewer SPICE
59 - 163 1F8A B 63 - 167 Jmol AstexViewer SPICE
1NMV A 59 - 163 Jmol AstexViewer SPICE
1NMW A 59 - 163 Jmol AstexViewer SPICE
1PIN A 59 - 163 Jmol AstexViewer SPICE
2ITK A 59 - 163 Jmol AstexViewer SPICE
2Q5A A 59 - 163 Jmol AstexViewer SPICE
2XP3 A 59 - 163 Jmol AstexViewer SPICE
2XP4 A 59 - 163 Jmol AstexViewer SPICE
2XP5 A 59 - 163 Jmol AstexViewer SPICE
2XP6 A 59 - 163 Jmol AstexViewer SPICE
2XP7 A 59 - 163 Jmol AstexViewer SPICE
2XP8 A 59 - 163 Jmol AstexViewer SPICE
2XP9 A 59 - 163 Jmol AstexViewer SPICE
2XPA A 59 - 163 Jmol AstexViewer SPICE
2XPB A 59 - 163 Jmol AstexViewer SPICE
2ZQS A 59 - 163 Jmol AstexViewer SPICE
2ZQT A 59 - 163 Jmol AstexViewer SPICE
2ZQU A 59 - 163 Jmol AstexViewer SPICE
2ZQV A 59 - 163 Jmol AstexViewer SPICE
2ZR4 A 59 - 163 Jmol AstexViewer SPICE
2ZR5 A 59 - 163 Jmol AstexViewer SPICE
2ZR6 A 59 - 163 Jmol AstexViewer SPICE
3I6C A 59 - 163 Jmol AstexViewer SPICE
B 59 - 163 Jmol AstexViewer SPICE
3IK8 A 59 - 163 Jmol AstexViewer SPICE
B 59 - 163 Jmol AstexViewer SPICE
3IKD A 59 - 163 Jmol AstexViewer SPICE
B 59 - 163 Jmol AstexViewer SPICE
3IKG A 59 - 163 Jmol AstexViewer SPICE
B 59 - 163 Jmol AstexViewer SPICE
3JYJ A 59 - 163 Jmol AstexViewer SPICE
B 59 - 163 Jmol AstexViewer SPICE
3KAB A 59 - 163 Jmol AstexViewer SPICE
3KAC A 59 - 163 Jmol AstexViewer SPICE
B 59 - 163 Jmol AstexViewer SPICE
3KAD A 59 - 163 Jmol AstexViewer SPICE
3KAF A 59 - 163 Jmol AstexViewer SPICE
3KAG A 59 - 163 Jmol AstexViewer SPICE
3KAH A 59 - 163 Jmol AstexViewer SPICE
3KAI A 59 - 163 Jmol AstexViewer SPICE
3KCE A 59 - 163 Jmol AstexViewer SPICE
3NTP A 59 - 163 Jmol AstexViewer SPICE
3ODK A 59 - 163 Jmol AstexViewer SPICE
3OOB A 59 - 163 Jmol AstexViewer SPICE
3TC5 A 59 - 163 Jmol AstexViewer SPICE
3TCZ A 59 - 163 Jmol AstexViewer SPICE
WW 7 - 37 1F8A B 11 - 41 Jmol AstexViewer SPICE
1I6C A 2 - 32 Jmol AstexViewer SPICE
1I8G B 2 - 32 Jmol AstexViewer SPICE
1I8H B 2 - 32 Jmol AstexViewer SPICE
1NMV A 7 - 37 Jmol AstexViewer SPICE
1PIN A 7 - 37 Jmol AstexViewer SPICE
1ZCN A 7 - 37 Jmol AstexViewer SPICE
2F21 A 7 - 37 Jmol AstexViewer SPICE
2ITK A 7 - 37 Jmol AstexViewer SPICE
2KBU A 2 - 29 Jmol AstexViewer SPICE
2KCF A 4 - 34 Jmol AstexViewer SPICE
2LB3 A 11 - 41 Jmol AstexViewer SPICE
2Q5A A 7 - 37 Jmol AstexViewer SPICE
2XP3 A 7 - 37 Jmol AstexViewer SPICE
2XP4 A 7 - 37 Jmol AstexViewer SPICE
2XP5 A 7 - 37 Jmol AstexViewer SPICE
2XP6 A 7 - 37 Jmol AstexViewer SPICE
2XP7 A 7 - 37 Jmol AstexViewer SPICE
2XP8 A 7 - 37 Jmol AstexViewer SPICE
2XP9 A 7 - 37 Jmol AstexViewer SPICE
2XPA A 7 - 37 Jmol AstexViewer SPICE
2XPB A 7 - 37 Jmol AstexViewer SPICE
2ZQS A 7 - 37 Jmol AstexViewer SPICE
2ZQT A 7 - 37 Jmol AstexViewer SPICE
2ZQU A 7 - 37 Jmol AstexViewer SPICE
2ZQV A 7 - 37 Jmol AstexViewer SPICE
2ZR4 A 7 - 37 Jmol AstexViewer SPICE
2ZR5 A 7 - 37 Jmol AstexViewer SPICE
2ZR6 A 7 - 37 Jmol AstexViewer SPICE
3KAB A 7 - 37 Jmol AstexViewer SPICE
3KAD A 7 - 37 Jmol AstexViewer SPICE
3KAF A 7 - 37 Jmol AstexViewer SPICE
3KAG A 7 - 37 Jmol AstexViewer SPICE
3KAH A 7 - 37 Jmol AstexViewer SPICE
3KAI A 7 - 37 Jmol AstexViewer SPICE
3KCE A 7 - 37 Jmol AstexViewer SPICE
3NTP A 7 - 37 Jmol AstexViewer SPICE
3ODK A 7 - 37 Jmol AstexViewer SPICE
3OOB A 7 - 37 Jmol AstexViewer SPICE
3TC5 A 7 - 37 Jmol AstexViewer SPICE
3TCZ A 7 - 37 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.