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6  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NCF4_HUMAN (Q15080)

Summary

This is the summary of UniProt entry NCF4_HUMAN (Q15080).

Description: Neutrophil cytosol factor 4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 339 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A PX 19 136
disorder n/a 158 159
disorder n/a 161 165
Pfam A SH3_1 176 221
Pfam A PB1 237 329

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15080. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVAQQLRAE SDFEQLPDDV AISANIADIE EKRGFTSHFV FVIEVKTKGG
50
51
SKYLIYRRYR QFHALQSKLE ERFGPDSKSS ALACTLPTLP AKVYVGVKQE
100
101
IAEMRIPALN AYMKSLLSLP VWVLMDEDVR IFFYQSPYDS EQVPQALRRL
150
151
RPRTRKVKSV SPQGNSVDRM AAPRAEALFD FTGNSKLELN FKAGDVIFLL
200
201
SRINKDWLEG TVRGATGIFP LSFVKILKDF PEEDDPTNWL RCYYYEDTIS
250
251
TIKDIAVEED LSSTPLLKDL LELTRREFQR EDIALNYRDA EGDLVRLLSD
300
301
EDVALMVRQA RGLPSQKRLF PWKLHITQKD NYRVYNTMP            
339
 

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Checksums:
CRC64:D82FE9E5BA12890B
MD5:2f1bc25168746d6cff0ced738b970c0f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PB1 237 - 328 2DYB B 237 - 328 Jmol AstexViewer SPICE
237 - 329 1OEY J 237 - 329 Jmol AstexViewer SPICE
K 237 - 329 Jmol AstexViewer SPICE
L 237 - 329 Jmol AstexViewer SPICE
M 237 - 329 Jmol AstexViewer SPICE
2DYB A 237 - 329 Jmol AstexViewer SPICE
PX 19 - 136 1H6H A 19 - 136 Jmol AstexViewer SPICE
2DYB A 19 - 136 Jmol AstexViewer SPICE
B 19 - 136 Jmol AstexViewer SPICE
SH3_1 176 - 221 1W6X A 176 - 221 Jmol AstexViewer SPICE
B 176 - 221 Jmol AstexViewer SPICE
1W70 A 176 - 221 Jmol AstexViewer SPICE
B 176 - 221 Jmol AstexViewer SPICE
1Z9Q A 9 - 54 Jmol AstexViewer SPICE
2DYB A 176 - 221 Jmol AstexViewer SPICE
B 176 - 221 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.