Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PTPA_HUMAN (Q15257)

Summary

This is the summary of UniProt entry PTPA_HUMAN (Q15257).

Description: Serine/threonine-protein phosphatase 2A activator EC=5.2.1.8
Source organism: Homo sapiens (Human)
Length: 358 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 27
low_complexity n/a 8 19
Pfam A PTPA 25 358
disorder n/a 81 82
low_complexity n/a 192 202

Show or hide domain scores.

Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

Note: it can take a few seconds for this image to be generated and loaded.

Loading feature alignment...

Show sources update panel.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15257. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEGERQPPP DSSEEAPPAT QNFIIPKKEI HTVPDMGKWK RSQAYADYIG
50
51
FILTLNEGVK GKKLTFEYRV SEMWNEVHEE KEQAAKQSVS CDECIPLPRA
100
101
GHCAPSEAIE KLVALLNTLD RWIDETPPVD QPSRFGNKAY RTWYAKLDEE
150
151
AENLVATVVP THLAAAVPEV AVYLKESVGN STRIDYGTGH EAAFAAFLCC
200
201
LCKIGVLRVD DQIAIVFKVF NRYLEVMRKL QKTYRMEPAG SQGVWGLDDF
250
251
QFLPFIWGSS QLIDHPYLEP RHFVDEKAVN ENHKDYMFLE CILFITEMKT
300
301
GPFAEHSNQL WNISAVPSWS KVNQGLIRMY KAECLEKFPV IQHFKFGSLL
350
351
PIHPVTSG                                              
358
 

Show the unformatted sequence.

Checksums:
CRC64:2A962521AF5B4CF7
MD5:c8be94a0755d7a19e9f723880a94dbe1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PTPA 25 - 357 2G62 A 25 - 322 Jmol AstexViewer SPICE
2HV6 A 25 - 322 Jmol AstexViewer SPICE
B 25 - 322 Jmol AstexViewer SPICE
2HV7 A 25 - 322 Jmol AstexViewer SPICE
B 25 - 322 Jmol AstexViewer SPICE
C 25 - 322 Jmol AstexViewer SPICE
D 25 - 322 Jmol AstexViewer SPICE
E 25 - 322 Jmol AstexViewer SPICE
F 25 - 322 Jmol AstexViewer SPICE
G 25 - 322 Jmol AstexViewer SPICE
H 25 - 322 Jmol AstexViewer SPICE
2IXM A 25 - 322 Jmol AstexViewer SPICE