Summary
This is the summary of UniProt entry RASA2_HUMAN (Q15283).
| Description: | Ras GTPase-activating protein 2 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 849 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 22 |
| low_complexity | n/a | 2 | 26 |
| disorder | n/a | 14 | 32 |
| Pfam A | C2 | 40 | 122 |
| Pfam A | C2 | 173 | 273 |
| disorder | n/a | 205 | 214 |
| low_complexity | n/a | 208 | 216 |
| disorder | n/a | 301 | 302 |
| Pfam A | RasGAP | 377 | 550 |
| low_complexity | n/a | 502 | 519 |
| low_complexity | n/a | 548 | 560 |
| low_complexity | n/a | 590 | 602 |
| disorder | n/a | 596 | 609 |
| Pfam A | PH | 605 | 705 |
| Pfam A | BTK | 712 | 743 |
| low_complexity | n/a | 826 | 840 |
| disorder | n/a | 828 | 833 |
| disorder | n/a | 838 | 842 |
| disorder | n/a | 848 | 849 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q15283. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MAAAAPAAAA ASSEAPAASA TAEPEAGDQD SREVRVLQSL RGKICEAKNL
50 51
LPYLGPHKMR DCFCTINLDQ EEVYRTQVVE KSLSPFFSEE FYFEIPRTFQ
100 101
YLSFYVYDKN VLQRDLRIGK VAIKKEDLCN HSGKETWFSL QPVDSNSEVQ
150 151
GKVHLELKLN ELITENGTVC QQLVVHIKAC HGLPLINGQS CDPYATVSLV
200 201
GPSRNDQKKT KVKKKTSNPQ FNEIFYFEVT RSSSYTRKSQ FQVEEEDIEK
250 251
LEIRIDLWNN GNLVQDVFLG EIKVPVNVLR TDSSHQAWYL LQPRDNGNKS
300 301
SKTDDLGSLR LNICYTEDYV LPSEYYGPLK TLLLKSPDVQ PISASAAYIL
350 351
SEICRDKNDA VLPLVRLLLH HDKLVPFATA VAELDLKDTQ DANTIFRGNS
400 401
LATRCLDEMM KIVGGHYLKV TLKPILDEIC DSSKSCEIDP IKLKEGDNVE
450 451
NNKENLRYYV DKLFNTIVKS SMSCPTVMCD IFYSLRQMAT QRFPNDPHVQ
500 501
YSAVSSFVFL RFFAVAVVSP HTFHLRPHHP DAQTIRTLTL ISKTIQTLGS
550 551
WGSLSKSKSS FKETFMCEFF KMFQEEGYII AVKKFLDEIS STETKESSGT
600 601
SEPVHLKEGE MYKRAQGRTR IGKKNFKKRW FCLTSRELTY HKQPGKDAIY
650 651
TIPVKNILAV EKLEESSFNK KNMFQVIHTE KPLYVQANNC VEANEWIDVL
700 701
CRVSRCNQNR LSFYHPSVYL NGNWLCCQET GENTLGCKPC TAGVPADIQI
750 751
DIDEDRETER IYSLFTLSLL KLQKMEEACG TIAVYQGPQK EPDDYSNFVI
800 801
EDSVTTFKTI QQIKSIIEKL DEPHEKYRKK RSSSAKYGSK ENPIVGKAS
849
Show the unformatted sequence. |
| Checksums: |
CRC64:A4B491DFF5C4CB76
MD5:09bd9228ac99b96d2939a21f525c2fa0
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.