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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PCBP1_HUMAN (Q15365)

Summary

This is the summary of UniProt entry PCBP1_HUMAN (Q15365).

Description: Poly(rC)-binding protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 356 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A KH_1 15 75
disorder n/a 40 42
disorder n/a 44 46
disorder n/a 85 91
Pfam A KH_1 99 162
disorder n/a 131 136
disorder n/a 176 182
disorder n/a 205 210
disorder n/a 216 221
disorder n/a 235 236
disorder n/a 271 272
Pfam A KH_1 281 343
disorder n/a 313 317

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15365. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDAGVTESGL NVTLTIRLLM HGKEVGSIIG KKGESVKRIR EESGARINIS
50
51
EGNCPERIIT LTGPTNAIFK AFAMIIDKLE EDINSSMTNS TAASRPPVTL
100
101
RLVVPATQCG SLIGKGGCKI KEIRESTGAQ VQVAGDMLPN STERAITIAG
150
151
VPQSVTECVK QICLVMLETL SQSPQGRVMT IPYQPMPASS PVICAGGQDR
200
201
CSDAAGYPHA THDLEGPPLD AYSIQGQHTI SPLDLAKLNQ VARQQSHFAM
250
251
MHGGTGFAGI DSSSPEVKGY WASLDASTQT THELTIPNNL IGCIIGRQGA
300
301
NINEIRQMSG AQIKIANPVE GSSGRQVTIT GSAASISLAQ YLINARLSSE
350
351
KGMGCS                                                
356
 

Show the unformatted sequence.

Checksums:
CRC64:6D1A261276CA206D
MD5:ffa53f6d7786a4d5076242015b213712

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
KH_1 15 - 75 1ZTG A 15 - 75 Jmol AstexViewer SPICE
B 15 - 75 Jmol AstexViewer SPICE
C 15 - 75 Jmol AstexViewer SPICE
D 15 - 75 Jmol AstexViewer SPICE
3VKE A 15 - 75 Jmol AstexViewer SPICE
B 15 - 75 Jmol AstexViewer SPICE
C 15 - 75 Jmol AstexViewer SPICE
D 15 - 75 Jmol AstexViewer SPICE
281 - 343 1WVN A 7 - 69 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.