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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KS6A1_HUMAN (Q15418)

Summary

This is the summary of UniProt entry KS6A1_HUMAN (Q15418).

Description: Ribosomal protein S6 kinase alpha-1 EC=2.7.11.1
Source organism: Homo sapiens (Human)
Length: 735 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 14 34
Pfam A Pkinase 62 321
disorder n/a 303 309
Pfam A Pkinase_C 341 384
disorder n/a 353 354
disorder n/a 360 369
disorder n/a 392 401
Pfam A Pkinase 418 675
disorder n/a 705 710
disorder n/a 713 722
disorder n/a 733 735

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15418. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPLAQLKEPW PLMELVPLDP ENGQTSGEEA GLQPSKDEGV LKEISITHHV
50
51
KAGSEKADPS HFELLKVLGQ GSFGKVFLVR KVTRPDSGHL YAMKVLKKAT
100
101
LKVRDRVRTK MERDILADVN HPFVVKLHYA FQTEGKLYLI LDFLRGGDLF
150
151
TRLSKEVMFT EEDVKFYLAE LALGLDHLHS LGIIYRDLKP ENILLDEEGH
200
201
IKLTDFGLSK EAIDHEKKAY SFCGTVEYMA PEVVNRQGHS HSADWWSYGV
250
251
LMFEMLTGSL PFQGKDRKET MTLILKAKLG MPQFLSTEAQ SLLRALFKRN
300
301
PANRLGSGPD GAEEIKRHVF YSTIDWNKLY RREIKPPFKP AVAQPDDTFY
350
351
FDTEFTSRTP KDSPGIPPSA GAHQLFRGFS FVATGLMEDD GKPRAPQAPL
400
401
HSVVQQLHGK NLVFSDGYVV KETIGVGSYS ECKRCVHKAT NMEYAVKVID
450
451
KSKRDPSEEI EILLRYGQHP NIITLKDVYD DGKHVYLVTE LMRGGELLDK
500
501
ILRQKFFSER EASFVLHTIG KTVEYLHSQG VVHRDLKPSN ILYVDESGNP
550
551
ECLRICDFGF AKQLRAENGL LMTPCYTANF VAPEVLKRQG YDEGCDIWSL
600
601
GILLYTMLAG YTPFANGPSD TPEEILTRIG SGKFTLSGGN WNTVSETAKD
650
651
LVSKMLHVDP HQRLTAKQVL QHPWVTQKDK LPQSQLSHQD LQLVKGAMAA
700
701
TYSALNSSKP TPQLKPIESS ILAQRRVRKL PSTTL                
735
 

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Checksums:
CRC64:765731A4442A53DF
MD5:b042873d6b5cb29dcaf26721af6c5995

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Pkinase 418 - 675 2WNT A 418 - 675 Jmol AstexViewer SPICE
B 418 - 675 Jmol AstexViewer SPICE
3RNY A 418 - 675 Jmol AstexViewer SPICE
419 - 675 3RNY B 419 - 675 Jmol AstexViewer SPICE
62 - 321 2Z7Q A 62 - 321 Jmol AstexViewer SPICE
2Z7R A 62 - 321 Jmol AstexViewer SPICE
2Z7S A 62 - 321 Jmol AstexViewer SPICE