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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FSCN1_HUMAN (Q16658)

Summary

This is the summary of UniProt entry FSCN1_HUMAN (Q16658).

Description: Fascin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 493 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Fascin 20 134
Pfam A Fascin 142 256
disorder n/a 199 200
disorder n/a 241 243
Pfam A Fascin 268 378
disorder n/a 274 295
Pfam A Fascin 391 493

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q16658. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKQIWTLEQ
50
51
PPDEAGSAAV CLRSHLGRYL AADKDGNVTC EREVPGPDCR FLIVAHDDGR
100
101
WSLQSEAHRR YFGGTEDRLS CFAQTVSPAE KWSVHIAMHP QVNIYSVTRK
150
151
RYAHLSARPA DEIAVDRDVP WGVDSLITLA FQDQRYSVQT ADHRFLRHDG
200
201
RLVARPEPAT GYTLEFRSGK VAFRDCEGRY LAPSGPSGTL KAGKATKVGK
250
251
DELFALEQSC AQVVLQAANE RNVSTRQGMD LSANQDEETD QETFQLEIDR
300
301
DTKKCAFRTH TGKYWTLTAT GGVQSTASSK NASCYFDIEW RDRRITLRAS
350
351
NGKFVTSKKN GQLAASVETA GDSELFLMKL INRPIIVFRG EHGFIGCRKV
400
401
TGTLDANRSS YDVFQLEFND GAYNIKDSTG KYWTVGSDSA VTSSGDTPVD
450
451
FFFEFCDYNK VAIKVGGRYL KGDHAGVLKA SAETVDPASL WEY       
493
 

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Checksums:
CRC64:C1453714BED6109A
MD5:74752ac735567b51f435866c8b2db26d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Fascin 142 - 256 1DFC A 1142 - 1256 Jmol AstexViewer SPICE
B 2142 - 2256 Jmol AstexViewer SPICE
3LLP A 142 - 256 Jmol AstexViewer SPICE
B 142 - 256 Jmol AstexViewer SPICE
3P53 A 142 - 256 Jmol AstexViewer SPICE
B 142 - 256 Jmol AstexViewer SPICE
20 - 134 1DFC A 1020 - 1134 Jmol AstexViewer SPICE
B 2020 - 2134 Jmol AstexViewer SPICE
3LLP A 20 - 134 Jmol AstexViewer SPICE
B 20 - 134 Jmol AstexViewer SPICE
3P53 A 20 - 134 Jmol AstexViewer SPICE
B 20 - 134 Jmol AstexViewer SPICE
268 - 378 1DFC A 1268 - 1378 Jmol AstexViewer SPICE
B 2268 - 2378 Jmol AstexViewer SPICE
3LLP A 268 - 378 Jmol AstexViewer SPICE
B 268 - 378 Jmol AstexViewer SPICE
3P53 A 268 - 378 Jmol AstexViewer SPICE
B 268 - 378 Jmol AstexViewer SPICE
391 - 493 1DFC A 1391 - 1493 Jmol AstexViewer SPICE
B 2391 - 2493 Jmol AstexViewer SPICE
3LLP A 391 - 493 Jmol AstexViewer SPICE
B 391 - 493 Jmol AstexViewer SPICE
3P53 A 391 - 493 Jmol AstexViewer SPICE
B 391 - 493 Jmol AstexViewer SPICE