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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: CAH9_HUMAN (Q16790)

Summary

This is the summary of UniProt entry CAH9_HUMAN (Q16790).

Description: Carbonic anhydrase 9 EC=4.2.1.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 459 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 37
disorder n/a 6 13
low_complexity n/a 6 21
disorder n/a 15 16
disorder n/a 25 27
low_complexity n/a 25 32
disorder n/a 34 158
low_complexity n/a 45 97
Pfam A Carb_anhydrase 132 390
disorder n/a 160 161
low_complexity n/a 187 196
disorder n/a 196 202
disorder n/a 204 210
disorder n/a 240 241
disorder n/a 290 295
transmembrane n/a 415 433
disorder n/a 444 452

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q16790. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAPLCPSPWL PLLIPAPAPG LTVQLLLSLL LLVPVHPQRL PRMQEDSPLG
50
51
GGSSGEDDPL GEEDLPSEED SPREEDPPGE EDLPGEEDLP GEEDLPEVKP
100
101
KSEEEGSLKL EDLPTVEAPG DPQEPQNNAH RDKEGDDQSH WRYGGDPPWP
150
151
RVSPACAGRF QSPVDIRPQL AAFCPALRPL ELLGFQLPPL PELRLRNNGH
200
201
SVQLTLPPGL EMALGPGREY RALQLHLHWG AAGRPGSEHT VEGHRFPAEI
250
251
HVVHLSTAFA RVDEALGRPG GLAVLAAFLE EGPEENSAYE QLLSRLEEIA
300
301
EEGSETQVPG LDISALLPSD FSRYFQYEGS LTTPPCAQGV IWTVFNQTVM
350
351
LSAKQLHTLS DTLWGPGDSR LQLNFRATQP LNGRVIEASF PAGVDSSPRA
400
401
AEPVQLNSCL AAGDILALVF GLLFAVTSVA FLVQMRRQHR RGTKGGVSYR
450
451
PAEVAETGA                                             
459
 

Show the unformatted sequence.

Checksums:
CRC64:BA67195483F0F5CE
MD5:8aad44f79eb8a4ecf08ddf34a53e7807

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Carb_anhydrase 138 - 390 3IAI A 2 - 260 Jmol AstexViewer SPICE
139 - 390 3IAI D 3 - 260 Jmol AstexViewer SPICE
140 - 390 3IAI B 4 - 260 Jmol AstexViewer SPICE
C 4 - 260 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.