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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CYP1_BRUMA (Q27450)

Summary

This is the summary of UniProt entry CYP1_BRUMA (Q27450).

Description: Peptidyl-prolyl cis-trans isomerase 1 EC=5.2.1.8
Source organism: Brugia malayi (Filarial nematode worm) (NCBI taxonomy ID 6279)
View Pfam proteome data.
Length: 843 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Pro_isomerase 10 175
low_complexity n/a 75 86
disorder n/a 110 112
disorder n/a 119 126
disorder n/a 155 156
disorder n/a 177 228
low_complexity n/a 185 218
coiled_coil n/a 207 227
disorder n/a 232 233
disorder n/a 235 344
disorder n/a 346 843
low_complexity n/a 394 407
coiled_coil n/a 530 550
coiled_coil n/a 665 685
Pfam B Pfam-B_35069 696 747
low_complexity n/a 700 736
low_complexity n/a 753 842

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q27450. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKKDRRRVF LDVTIDGNLA GRIVMELYND IAPRTCNNFL MLCTGMAGTG
50
51
KISGKPLHYK GSTFHRVIKN FMIQGGDFTK GDGTGGESIY GGMFDDEEFV
100
101
MKHDEPFVVS MANKGPNTNG SQFFITTTPA PHLNNIHVVF GKVVSGQEVV
150
151
TKIEYLKTNS KNRPLADVVI LNCGELVRRK KRQHSSRSNE SVSSSTSTEK
200
201
SHKKTKKTKM KEKKRKESDE VEQLEIGTVV PEAELQLSSV KAEDLPDEPD
250
251
HQNKYLMRRS KTPENSRKGK KEKQRQSPHR FSRRDIGHRL NRMRRTRTGH
300
301
KIKGRGALRF RTPEGSSDHD GSRTPPHWRR EQNRVITLDE LHRLQEKRKA
350
351
YELEELENPK NDVVDKAKTG ILLNTSEKIE DKEERYRGKS EKKENRHERS
400
401
RHTTRRSPEH VTRHFVKEKN RHKVDEVGNS EDMKQTKRDR RGRADEKEKV
450
451
EVNGEKAAAM DELNLDEPTV EVTLDSAEDI RDSDDEAIRI HLLKAKKMAE
500
501
EKTKQEAKML EKTGDKEGRD QKTISEAKQK DSAEKDRQHR EHKNDELEKR
550
551
AIEKQDKDQI VERDTGSKQR RKSDSKEHRG KTDRKHRSKS IEEDGRRSTS
600
601
REKLDDLKRK ETSGQKSQAD SEQTVEAKTN VVDSNSDNSK MSVNGKLKEV
650
651
SSTNKENEVS EQKDLKAEST KSEEIKQQVN EVSRKQKGGE KPKEHKRNER
700
701
SRSRRRRSRS NGRRRRSSSR RSRSRDRRHK SRSRSRGYVR RFEGWSRSRR
750
751
PTRRELYDER MRRERERRRS FDRYSDRRRT RSRSARRDSD RHSRRSRKRS
800
801
PSSSSSSSES SSSDSRSTAS SSASSKRSSS SDSSRSSRSR SSN       
843
 

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Checksums:
CRC64:3C34EC90A32EDBDC
MD5:e9f3d401dd08936ae8e5324f9e04c298

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Pro_isomerase 10 - 175 1A33 A 10 - 175 Jmol AstexViewer SPICE
1A58 A 10 - 175 Jmol AstexViewer SPICE
1C5F A 10 - 175 Jmol AstexViewer SPICE
C 10 - 175 Jmol AstexViewer SPICE
E 10 - 175 Jmol AstexViewer SPICE
G 10 - 175 Jmol AstexViewer SPICE
I 10 - 175 Jmol AstexViewer SPICE
K 10 - 175 Jmol AstexViewer SPICE
M 10 - 175 Jmol AstexViewer SPICE
O 10 - 175 Jmol AstexViewer SPICE