Summary
This is the summary of UniProt entry CYP1_BRUMA (Q27450).
| Description: | Peptidyl-prolyl cis-trans isomerase 1 EC=5.2.1.8 |
| Source organism: |
Brugia malayi (Filarial nematode worm)
(NCBI taxonomy ID
6279)
View Pfam proteome data. |
| Length: | 843 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Pro_isomerase | 10 | 175 |
| low_complexity | n/a | 75 | 86 |
| disorder | n/a | 110 | 112 |
| disorder | n/a | 119 | 126 |
| disorder | n/a | 155 | 156 |
| disorder | n/a | 177 | 228 |
| low_complexity | n/a | 185 | 218 |
| coiled_coil | n/a | 207 | 227 |
| disorder | n/a | 232 | 233 |
| disorder | n/a | 235 | 344 |
| disorder | n/a | 346 | 843 |
| low_complexity | n/a | 394 | 407 |
| coiled_coil | n/a | 530 | 550 |
| coiled_coil | n/a | 665 | 685 |
| Pfam B | Pfam-B_35069 | 696 | 747 |
| low_complexity | n/a | 700 | 736 |
| low_complexity | n/a | 753 | 842 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q27450. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSKKDRRRVF LDVTIDGNLA GRIVMELYND IAPRTCNNFL MLCTGMAGTG
50 51
KISGKPLHYK GSTFHRVIKN FMIQGGDFTK GDGTGGESIY GGMFDDEEFV
100 101
MKHDEPFVVS MANKGPNTNG SQFFITTTPA PHLNNIHVVF GKVVSGQEVV
150 151
TKIEYLKTNS KNRPLADVVI LNCGELVRRK KRQHSSRSNE SVSSSTSTEK
200 201
SHKKTKKTKM KEKKRKESDE VEQLEIGTVV PEAELQLSSV KAEDLPDEPD
250 251
HQNKYLMRRS KTPENSRKGK KEKQRQSPHR FSRRDIGHRL NRMRRTRTGH
300 301
KIKGRGALRF RTPEGSSDHD GSRTPPHWRR EQNRVITLDE LHRLQEKRKA
350 351
YELEELENPK NDVVDKAKTG ILLNTSEKIE DKEERYRGKS EKKENRHERS
400 401
RHTTRRSPEH VTRHFVKEKN RHKVDEVGNS EDMKQTKRDR RGRADEKEKV
450 451
EVNGEKAAAM DELNLDEPTV EVTLDSAEDI RDSDDEAIRI HLLKAKKMAE
500 501
EKTKQEAKML EKTGDKEGRD QKTISEAKQK DSAEKDRQHR EHKNDELEKR
550 551
AIEKQDKDQI VERDTGSKQR RKSDSKEHRG KTDRKHRSKS IEEDGRRSTS
600 601
REKLDDLKRK ETSGQKSQAD SEQTVEAKTN VVDSNSDNSK MSVNGKLKEV
650 651
SSTNKENEVS EQKDLKAEST KSEEIKQQVN EVSRKQKGGE KPKEHKRNER
700 701
SRSRRRRSRS NGRRRRSSSR RSRSRDRRHK SRSRSRGYVR RFEGWSRSRR
750 751
PTRRELYDER MRRERERRRS FDRYSDRRRT RSRSARRDSD RHSRRSRKRS
800 801
PSSSSSSSES SSSDSRSTAS SSASSKRSSS SDSSRSSRSR SSN
843
Show the unformatted sequence. |
| Checksums: |
CRC64:3C34EC90A32EDBDC
MD5:e9f3d401dd08936ae8e5324f9e04c298
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Pro_isomerase | 10 - 175 | 1A33 | A | 10 - 175 | Jmol AstexViewer SPICE |
| 1A58 | A | 10 - 175 | Jmol AstexViewer SPICE | ||
| 1C5F | A | 10 - 175 | Jmol AstexViewer SPICE | ||
| C | 10 - 175 | Jmol AstexViewer SPICE | |||
| E | 10 - 175 | Jmol AstexViewer SPICE | |||
| G | 10 - 175 | Jmol AstexViewer SPICE | |||
| I | 10 - 175 | Jmol AstexViewer SPICE | |||
| K | 10 - 175 | Jmol AstexViewer SPICE | |||
| M | 10 - 175 | Jmol AstexViewer SPICE | |||
| O | 10 - 175 | Jmol AstexViewer SPICE |