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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TMEDA_RABIT (Q28735)

Summary

This is the summary of UniProt entry TMEDA_RABIT (Q28735).

Description: Transmembrane emp24 domain-containing protein 10
Source organism: Oryctolagus cuniculus (Rabbit) (NCBI taxonomy ID 9986)
View Pfam proteome data.
Length: 219 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 31
low_complexity n/a 12 26
Pfam A EMP24_GP25L 31 213
disorder n/a 173 174
transmembrane n/a 186 208

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q28735. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGWSGPLAR RGPGPLALLF LFLLGPSSVL AISFHLPVNS RKCLREEIHK
50
51
DLLVTGAYEI TDQSGGAGGL RTHLKITDSA GHILYSKEDA SKGKFAFTTE
100
101
DYDMFEVCFE SKGTGRIPDQ LVILDMKHGV EAKNYEEIAK VEKLKPLEVE
150
151
LRRLEDLSES IVNDFAYMKK REEEMRDTNE STNTRVLYFS IFSMFCLIGL
200
201
ATWQVFYLRR FFKAKKLIE                                  
219
 

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Checksums:
CRC64:5AFA700D0A4DAB4C
MD5:abaf61dd7d2a7edc5ad5b82153b87714

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EMP24_GP25L 207 - 213 1M23 A 1 - 7 Jmol AstexViewer SPICE
1P23 A 2 - 8 Jmol AstexViewer SPICE
B 2 - 8 Jmol AstexViewer SPICE
C 2 - 8 Jmol AstexViewer SPICE
D 2 - 8 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.