Summary
This is the summary of UniProt entry CDK12_RAT (Q3MJK5).
| Description: | Cyclin-dependent kinase 12 EC=2.7.11.22 EC=2.7.11.23 |
| Source organism: |
Rattus norvegicus (Rat)
(NCBI taxonomy ID
10116)
View Pfam proteome data. |
| Length: | 1484 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 703 |
| low_complexity | n/a | 8 | 32 |
| low_complexity | n/a | 40 | 51 |
| low_complexity | n/a | 74 | 86 |
| low_complexity | n/a | 103 | 123 |
| low_complexity | n/a | 124 | 135 |
| low_complexity | n/a | 166 | 182 |
| low_complexity | n/a | 214 | 227 |
| low_complexity | n/a | 286 | 384 |
| low_complexity | n/a | 396 | 414 |
| low_complexity | n/a | 506 | 521 |
| low_complexity | n/a | 523 | 575 |
| low_complexity | n/a | 623 | 633 |
| low_complexity | n/a | 666 | 684 |
| disorder | n/a | 705 | 707 |
| Pfam A | Pkinase | 723 | 1016 |
| disorder | n/a | 1016 | 1017 |
| disorder | n/a | 1032 | 1039 |
| disorder | n/a | 1046 | 1104 |
| disorder | n/a | 1127 | 1367 |
| coiled_coil | n/a | 1139 | 1159 |
| low_complexity | n/a | 1252 | 1276 |
| disorder | n/a | 1369 | 1399 |
| disorder | n/a | 1402 | 1405 |
| disorder | n/a | 1412 | 1415 |
| disorder | n/a | 1417 | 1484 |
| low_complexity | n/a | 1465 | 1484 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q3MJK5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MPNSERHGGK KDGSGGASGT SQPSSGGGSS NSRERHRLVS KHKRHKSKHS
50 51
KDMGLVTPEA ASLGTIIKPL VEYDDISSDS DTFSDDMAFK SDRRENDERR
100 101
GTDRSDRLHR HRHHQHRRSR DLLKTKQTEK EKNQEVSKSG SMKDRLSGSS
150 151
KRSVEGNDDY GKAQLSKSSS KESRSSKMHK EKTRKERELK SGHKDRSKSH
200 201
RKRETPKSYK TVDSPKRRSR SPHRKWSDSS KQDDSPSGAS YGQDYDLSPP
250 251
RSHTSSNYDS YKKSPGSTSR RQSISPPYKE PSAYQSSTRS PSPYSRRQRS
300 301
VSPYSRRRSS SYERSGSYSG RSPSPYGRRR SSSPFLSKRS LSRSPISSRK
350 351
SMKSRSRSPA YSRHSSSHSK KKRSGSRSRH SSISPVRLPL NSSLGAELSR
400 401
KKKERAAAAA AAKLDGKESK GSPIILPKKE KFEVKESGLE SKKLPRGIKS
450 451
EKSTPDTELV NVAHSNTEVK NCLDTGKVKL DENLQKHPVK DLKAQGTKDT
500 501
KPVALKEVIV TSKETETSEK EALPPLPTIT SPPPLPSTTP PPQTPPLPPL
550 551
PPLPAVPLQP PLPPPQPPFS QVPVSNTSTL PSSPHPRTST LSSQTNSQPL
600 601
VQVSMKTQLS VTAAIPHLKT STLPPLPLPP LLPGDDDMDS PKEMLPSKPA
650 651
KKEKEQRTRH LLTDLPLPPE LPGGDPSPPD SPEPKAITPP QQPYKKRPKI
700 701
CCPRYGERRQ TESDWGKRCV DKFDIIGIIG EGTYGQVYKA KDKDTGELVA
750 751
LKKVRLDNEK EGFPITAIRE IKILRQLVHQ SVVNMKEIVT DKQDALDFKK
800 801
DKGAFYLVFE YMDHDLMGLL ESGLVHFSED HIKSFMKQLM EGLDYCHKKN
850 851
FLHRDIKCSN ILLNNSGQIK LADFGLARLY NSEESRPYTN KVITLWYRPP
900 901
ELLLGEERYT PAIDVWSCGC ILGELFTKKP IFQANLELAQ LELISRLCGS
950 951
PCPAVWPDVI KLPYFNTMKP KKQYRRRLRE EFSFIPSAAL DLLDHMLTLD
1000 1001
PSKRCTAEQT LQSDFLKDVE LSKMAPPDLP HWQDCHELWS KKRRRQRQSG
1050 1051
IVIEEQPPSK ASRKETTSGT AAEPVKNSSP APPQPAPVKA EPGPGDAVGL
1100 1101
GDITQQLNQS ELAVLLNLLQ SQTDLSIPQM AQLLNIHSNP EMQQQLEALN
1150 1151
QSISALTEAS SQQQDSESIA PEESLKEVPS VSVVLPPAEQ TTPEASNTPA
1200 1201
DMQNMLAVLL SQLMKTQEPA GNLEENTSDK NSGPQGPRRT PTMPQEEAAA
1250 1251
CPPHILPPEK RPPEPPGPPP PPPPPPLVEG DLSSAPQELN PAVTAALLQL
1300 1301
LSQPEAEPPG HLPHEHQALR PMEYSTRSHP NRTYGNTDGP ETGFSATDTD
1350 1351
ERSSGPALTE SLVQTLVKNR TFSGSVSHLG ESNSYQGTGS VQFPGDQDLR
1400 1401
FTRVPLALHS VVGQPFLKSE GNSNSVVHAE TKLQNYGELG PGTTGANSSG
1450 1451
TTLQWGGPAQ SFGKPYRGAA RVPPRGGRGR GVPY
1484
Show the unformatted sequence. |
| Checksums: |
CRC64:E3B346EA6A587D7B
MD5:8fa6a2a961f2f7d723dad8d155bda416
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.