Summary
This is the summary of UniProt entry IQGA2_MOUSE (Q3UQ44).
| Description: | Ras GTPase-activating-like protein IQGAP2 |
| Source organism: |
Mus musculus (Mouse)
(NCBI taxonomy ID
10090)
View Pfam proteome data. |
| Length: | 1575 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 5 |
| Pfam B | Pfam-B_53003 | 4 | 38 |
| disorder | n/a | 10 | 11 |
| disorder | n/a | 20 | 22 |
| disorder | n/a | 24 | 25 |
| Pfam A | CH | 44 | 156 |
| low_complexity | n/a | 57 | 67 |
| coiled_coil | n/a | 165 | 192 |
| low_complexity | n/a | 257 | 273 |
| disorder | n/a | 271 | 273 |
| disorder | n/a | 324 | 325 |
| low_complexity | n/a | 469 | 480 |
| Pfam B | Pfam-B_3506 | 471 | 639 |
| disorder | n/a | 596 | 597 |
| Pfam A | IQ | 691 | 711 |
| Pfam A | IQ | 721 | 741 |
| low_complexity | n/a | 800 | 812 |
| coiled_coil | n/a | 804 | 824 |
| Pfam A | RasGAP | 938 | 1150 |
| disorder | n/a | 1252 | 1274 |
| disorder | n/a | 1317 | 1362 |
| disorder | n/a | 1364 | 1366 |
| Pfam A | RasGAP_C | 1366 | 1501 |
| disorder | n/a | 1371 | 1385 |
| coiled_coil | n/a | 1411 | 1438 |
| disorder | n/a | 1412 | 1413 |
| disorder | n/a | 1460 | 1469 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q3UQ44. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MPHEELPSLQ RPRYGSIVDD ERLSAEEMDE RRRQNIAYEY LCHLEEAKRW
50 51
MEVCLVEELP PTTELEEGLR NGVYLAKLAK FFAPKMVSEK KIYDVEQTRY
100 101
KKSGLHFRHT DNTVQWLRAM EAIGLPKIFY PETTDVYDRK NIPRMIYCIH
150 151
ALSLYLFKLG IAPQIQDLLG KVDFTEEEIS NMRKELEKYG IQMPAFSKIG
200 201
GILANELSVD EAALHAAVIA INEAIEKGVA KQTIITLRNP NAVLTCVDDS
250 251
LSQEYQKELW EAKKKKEESA KLKNSCISEE ERDAYEELLT QAEIQSNIST
300 301
VNRMAAVDHI NAVLQEGDPE NTLLALKKPE AQLPAVYPFA AVMYQNELFN
350 351
LQKQNTSNYL AHEELLIAVE MLSAVALLNQ ALESSDLVAV QNQLRSPTIG
400 401
FNNLDEAHVD RYADALLSVK QEALSQGQDT LSWNEIQNCI DMINNQIQEE
450 451
NDRMVVLGYI NEAIDAGNPL KTLDTLLLPT ANIRDVDPDC AQHYQDVLFY
500 501
TKSQKLGDPK NVSKVLWLDE IQQAINEANV DENRAKQWVT LVVDVNECLD
550 551
RKQSDHILTA LKSSPSNIHN ILPECANKYY DTLVKAKESK TDNESSEGSW
600 601
VTLNVQEKYN YYYNTDSKEG SWVPPELCLS KESWLTGEEI EDIVEEVTSD
650 651
YIREKLWSAS EDLLVRFEAT TLGPALREEF EARKAFLYEQ TESVVKIQAF
700 701
WKGFKQRQEY LHRQQVFAGN VDSVVKIQSW FRMVTARKSY LSRLRYFEDH
750 751
KNEIVKIQSL LRASKARDDY KALVGSENPP LTVIRKFVYL LDQSDLDFQE
800 801
ELEVARLREE VVTKIRANQQ LEKDLNLMDI KIGLLVKNRI TLEDVISHRK
850 851
KLNKKKGGEI EILNNTDNKG IKSLSKERRK TLETYQQLFY LLQTKPSYLA
900 901
KLIFQMPQNK STKFMDTVIF TLYNYASNQR EEYLLLKLFK TALEEEIKSK
950 951
VDQVQDIVTG NPTVIKMVVS FNRGARGQNT LRQLLAPVVK EIIEDKALVI
1000 1001
NTNPVEVYKA WVNQLETQTG EASKLPYDVT TEQALTYPEV KNKLEASIEN
1050 1051
LRKVTDKVLG SIISSLDLLP YGLRYIAKVL KNSIREKFPD ATEEELLKIV
1100 1101
GNLLYYRYMN PAIVAPDGFD IIDMTAGGQI NSNQRRNLGS VAKVLQHAAS
1150 1151
NKLFEGENEH LSSMNNYLSE TYQEFRKYFQ EACDVPEPEE KFNMDKYTDL
1200 1201
VTVSKPVIYI SIEEIINTHL LLLEHQDAIA TEKSDLLNEL LESLGEVPTV
1250 1251
ESFLGEGAVD PNDPNKENTL NQLSKTEISL SLTSKYDVKD GEAVDGRSLM
1300 1301
IKTKKLIIDV TRNQPGSTLT EILETPATGQ QELEHAKDME SRAVVDSRTP
1350 1351
EEGKQSQAVI EDARLPLEQK KRKIQRNLRT LEQTGHVSSK NKYQDILNEI
1400 1401
AKDIRNQRIH RKLRKAELSK LQQTLNALNK KAAFYEDQIN YYDTYIKTCV
1450 1451
DNLKRKNSRR SIKLDGKAEP KGTKRVKPVR YTAAKLHDKG VLLGIDDLQT
1500 1501
NQFKNVMFDI IATEDMGIFD VRSKFLGVEM EKVQLNIQDL LQMQYEGVAV
1550 1551
MKMFDKVKVN VNLLIYLLNK KFYGK
1575
Show the unformatted sequence. |
| Checksums: |
CRC64:5EF176042E4D158F
MD5:01b7ef81108e975f4ce259b9ae587aad
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.