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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: S22A6_HUMAN (Q4U2R8)

Summary

This is the summary of UniProt entry S22A6_HUMAN (Q4U2R8).

Description: Solute carrier family 22 member 6
Source organism: Homo sapiens (Human)
Length: 563 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Sugar_tr 98 518
transmembrane n/a 136 155
transmembrane n/a 167 187
transmembrane n/a 193 213
transmembrane n/a 225 244
transmembrane n/a 250 269
low_complexity n/a 258 268
transmembrane n/a 337 356
transmembrane n/a 368 389
transmembrane n/a 396 415
low_complexity n/a 400 405
transmembrane n/a 421 444
transmembrane n/a 456 475
transmembrane n/a 487 504
disorder n/a 515 521
disorder n/a 530 539
disorder n/a 543 554
disorder n/a 561 563

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q4U2R8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAFNDLLQQV GGVGRFQQIQ VTLVVLPLLL MASHNTLQNF TAAIPTHHCR
50
51
PPADANLSKN GGLEVWLPRD RQGQPESCLR FTSPQWGLPF LNGTEANGTG
100
101
ATEPCTDGWI YDNSTFPSTI VTEWDLVCSH RALRQLAQSL YMVGVLLGAM
150
151
VFGYLADRLG RRKVLILNYL QTAVSGTCAA FAPNFPIYCA FRLLSGMALA
200
201
GISLNCMTLN VEWMPIHTRA CVGTLIGYVY SLGQFLLAGV AYAVPHWRHL
250
251
QLLVSAPFFA FFIYSWFFIE SARWHSSSGR LDLTLRALQR VARINGKREE
300
301
GAKLSMEVLR ASLQKELTMG KGQASAMELL RCPTLRHLFL CLSMLWFATS
350
351
FAYYGLVMDL QGFGVSIYLI QVIFGAVDLP AKLVGFLVIN SLGRRPAQMA
400
401
ALLLAGICIL LNGVIPQDQS IVRTSLAVLG KGCLAASFNC IFLYTGELYP
450
451
TMIRQTGMGM GSTMARVGSI VSPLVSMTAE LYPSMPLFIY GAVPVAASAV
500
501
TVLLPETLGQ PLPDTVQDLE SRWAPTQKEA GIYPRKGKQT RQQQEHQKYM
550
551
VPLQASAQEK NGL                                        
563
 

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Checksums:
CRC64:74AD3EA2678032E4
MD5:35d0b55c7a32896a8dc823a1533c59e9

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.