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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CAH4_MOUSE (Q64444)

Summary

This is the summary of UniProt entry CAH4_MOUSE (Q64444).

Description: Carbonic anhydrase 4 EC=4.2.1.1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 305 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 3 11
Pfam A Carb_anhydrase 22 278
disorder n/a 37 41
disorder n/a 52 54
disorder n/a 56 57
disorder n/a 85 86
disorder n/a 119 122
disorder n/a 126 129
disorder n/a 184 185
disorder n/a 187 189
disorder n/a 191 198
disorder n/a 261 263
low_complexity n/a 283 299

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q64444. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQLLLALLAL AYVAPSTEDS GWCYEIQTKD PRSSCLGPEK WPGACKENQQ
50
51
SPINIVTART KVNPRLTPFI LVGYDQKQQW PIKNNQHTVE MTLGGGACII
100
101
GGDLPARYEA VQLHLHWSNG NDNGSEHSID GRHFAMEMHI VHKKLTSSKE
150
151
DSKDKFAVLA FMIEVGDKVN KGFQPLVEAL PSISKPHSTS TVRESSLQDM
200
201
LPPSTKMYTY FRYNGSLTTP NCDETVIWTV YKQPIKIHKN QFLEFSKNLY
250
251
YDEDQKLNMK DNVRPLQPLG KRQVFKSHAP GQLLSLPLPT LLVPTLTCLV
300
301
ANFLQ                                                 
305
 

Show the unformatted sequence.

Checksums:
CRC64:EEE988FF52732884
MD5:1e44bd7c3cfae9d062f90462cdc4089d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Carb_anhydrase 22 - 278 2ZNC A 5 - 260 Jmol AstexViewer SPICE
3ZNC A 5 - 260 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.