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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PKN3_HUMAN (Q6P5Z2)

Summary

This is the summary of UniProt entry PKN3_HUMAN (Q6P5Z2).

Description: Serine/threonine-protein kinase N3 EC=2.7.11.13
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 889 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 21
Pfam A HR1 18 84
disorder n/a 25 26
disorder n/a 35 59
coiled_coil n/a 57 77
disorder n/a 61 62
disorder n/a 64 66
disorder n/a 74 104
low_complexity n/a 81 95
Pfam A HR1 105 177
disorder n/a 118 145
disorder n/a 165 184
low_complexity n/a 172 183
Pfam A HR1 178 249
coiled_coil n/a 208 242
disorder n/a 212 220
low_complexity n/a 214 227
low_complexity n/a 229 249
disorder n/a 247 248
disorder n/a 251 276
disorder n/a 299 300
low_complexity n/a 299 309
disorder n/a 313 318
low_complexity n/a 463 474
disorder n/a 468 553
low_complexity n/a 509 522
low_complexity n/a 543 555
Pfam A Pkinase 559 818
Pfam A Pkinase_C 838 885
low_complexity n/a 853 870
disorder n/a 863 864

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6P5Z2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEEGAPRQPG PSQWPPEDEK EVIRRAIQKE LKIKEGVENL RRVATDRRHL
50
51
GHVQQLLRSS NRRLEQLHGE LRELHARILL PGPGPGPAEP VASGPRPWAE
100
101
QLRARHLEAL RRQLHVELKV KQGAENMTHT CASGTPKERK LLAAAQQMLR
150
151
DSQLKVALLR MKISSLEASG SPEPGPELLA EELQHRLHVE AAVAEGAKNV
200
201
VKLLSSRRTQ DRKALAEAQA QLQESSQKLD LLRLALEQLL EQLPPAHPLR
250
251
SRVTRELRAA VPGYPQPSGT PVKPTALTGT LQVRLLGCEQ LLTAVPGRSP
300
301
AAALASSPSE GWLRTKAKHQ RGRGELASEV LAVLKVDNRV VGQTGWGQVA
350
351
EQSWDQTFVI PLERARELEI GVHWRDWRQL CGVAFLRLED FLDNACHQLS
400
401
LSLVPQGLLF AQVTFCDPVI ERRPRLQRQE RIFSKRRGQD FLRASQMNLG
450
451
MAAWGRLVMN LLPPCSSPST ISPPKGCPRT PTTLREASDP ATPSNFLPKK
500
501
TPLGEEMTPP PKPPRLYLPQ EPTSEETPRT KRPHMEPRTR RGPSPPASPT
550
551
RKPPRLQDFR CLAVLGRGHF GKVLLVQFKG TGKYYAIKAL KKQEVLSRDE
600
601
IESLYCEKRI LEAVGCTGHP FLLSLLACFQ TSSHACFVTE FVPGGDLMMQ
650
651
IHEDVFPEPQ ARFYVACVVL GLQFLHEKKI IYRDLKLDNL LLDAQGFLKI
700
701
ADFGLCKEGI GFGDRTSTFC GTPEFLAPEV LTQEAYTRAV DWWGLGVLLY
750
751
EMLVGECPFP GDTEEEVFDC IVNMDAPYPG FLSVQGLEFI QKLLQKCPEK
800
801
RLGAGEQDAE EIKVQPFFRT TNWQALLART IQPPFVPTLC GPADLRYFEG
850
851
EFTGLPPALT PPAPHSLLTA RQQAAFRDFD FVSERFLEP            
889
 

Show the unformatted sequence.

Checksums:
CRC64:F3891DA1420DF54E
MD5:325537b4b59b32e56d833b4c9be42f82

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.