Summary
This is the summary of UniProt entry PKN3_HUMAN (Q6P5Z2).
| Description: | Serine/threonine-protein kinase N3 EC=2.7.11.13 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 889 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 21 |
| Pfam A | HR1 | 18 | 84 |
| disorder | n/a | 25 | 26 |
| disorder | n/a | 35 | 59 |
| coiled_coil | n/a | 57 | 77 |
| disorder | n/a | 61 | 62 |
| disorder | n/a | 64 | 66 |
| disorder | n/a | 74 | 104 |
| low_complexity | n/a | 81 | 95 |
| Pfam A | HR1 | 105 | 177 |
| disorder | n/a | 118 | 145 |
| disorder | n/a | 165 | 184 |
| low_complexity | n/a | 172 | 183 |
| Pfam A | HR1 | 178 | 249 |
| coiled_coil | n/a | 208 | 242 |
| disorder | n/a | 212 | 220 |
| low_complexity | n/a | 214 | 227 |
| low_complexity | n/a | 229 | 249 |
| disorder | n/a | 247 | 248 |
| disorder | n/a | 251 | 276 |
| disorder | n/a | 299 | 300 |
| low_complexity | n/a | 299 | 309 |
| disorder | n/a | 313 | 318 |
| low_complexity | n/a | 463 | 474 |
| disorder | n/a | 468 | 553 |
| low_complexity | n/a | 509 | 522 |
| low_complexity | n/a | 543 | 555 |
| Pfam A | Pkinase | 559 | 818 |
| Pfam A | Pkinase_C | 838 | 885 |
| low_complexity | n/a | 853 | 870 |
| disorder | n/a | 863 | 864 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q6P5Z2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MEEGAPRQPG PSQWPPEDEK EVIRRAIQKE LKIKEGVENL RRVATDRRHL
50 51
GHVQQLLRSS NRRLEQLHGE LRELHARILL PGPGPGPAEP VASGPRPWAE
100 101
QLRARHLEAL RRQLHVELKV KQGAENMTHT CASGTPKERK LLAAAQQMLR
150 151
DSQLKVALLR MKISSLEASG SPEPGPELLA EELQHRLHVE AAVAEGAKNV
200 201
VKLLSSRRTQ DRKALAEAQA QLQESSQKLD LLRLALEQLL EQLPPAHPLR
250 251
SRVTRELRAA VPGYPQPSGT PVKPTALTGT LQVRLLGCEQ LLTAVPGRSP
300 301
AAALASSPSE GWLRTKAKHQ RGRGELASEV LAVLKVDNRV VGQTGWGQVA
350 351
EQSWDQTFVI PLERARELEI GVHWRDWRQL CGVAFLRLED FLDNACHQLS
400 401
LSLVPQGLLF AQVTFCDPVI ERRPRLQRQE RIFSKRRGQD FLRASQMNLG
450 451
MAAWGRLVMN LLPPCSSPST ISPPKGCPRT PTTLREASDP ATPSNFLPKK
500 501
TPLGEEMTPP PKPPRLYLPQ EPTSEETPRT KRPHMEPRTR RGPSPPASPT
550 551
RKPPRLQDFR CLAVLGRGHF GKVLLVQFKG TGKYYAIKAL KKQEVLSRDE
600 601
IESLYCEKRI LEAVGCTGHP FLLSLLACFQ TSSHACFVTE FVPGGDLMMQ
650 651
IHEDVFPEPQ ARFYVACVVL GLQFLHEKKI IYRDLKLDNL LLDAQGFLKI
700 701
ADFGLCKEGI GFGDRTSTFC GTPEFLAPEV LTQEAYTRAV DWWGLGVLLY
750 751
EMLVGECPFP GDTEEEVFDC IVNMDAPYPG FLSVQGLEFI QKLLQKCPEK
800 801
RLGAGEQDAE EIKVQPFFRT TNWQALLART IQPPFVPTLC GPADLRYFEG
850 851
EFTGLPPALT PPAPHSLLTA RQQAAFRDFD FVSERFLEP
889
Show the unformatted sequence. |
| Checksums: |
CRC64:F3891DA1420DF54E
MD5:325537b4b59b32e56d833b4c9be42f82
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.