Summary
This is the summary of UniProt entry SULF2_HUMAN (Q8IWU5).
| Description: | Extracellular sulfatase Sulf-2 EC=3.1.6.- |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 870 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 24 |
| low_complexity | n/a | 16 | 27 |
| Pfam A | Sulfatase | 44 | 375 |
| disorder | n/a | 112 | 115 |
| disorder | n/a | 231 | 235 |
| disorder | n/a | 237 | 238 |
| low_complexity | n/a | 520 | 528 |
| Pfam A | DUF3740 | 527 | 665 |
| disorder | n/a | 560 | 586 |
| coiled_coil | n/a | 628 | 655 |
| disorder | n/a | 646 | 650 |
| coiled_coil | n/a | 697 | 717 |
| low_complexity | n/a | 697 | 715 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IWU5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MGPPSLVLCL LSATVFSLLG GSSAFLSHHR LKGRFQRDRR NIRPNIILVL
50 51
TDDQDVELGS MQVMNKTRRI MEQGGAHFIN AFVTTPMCCP SRSSILTGKY
100 101
VHNHNTYTNN ENCSSPSWQA QHESRTFAVY LNSTGYRTAF FGKYLNEYNG
150 151
SYVPPGWKEW VGLLKNSRFY NYTLCRNGVK EKHGSDYSKD YLTDLITNDS
200 201
VSFFRTSKKM YPHRPVLMVI SHAAPHGPED SAPQYSRLFP NASQHITPSY
250 251
NYAPNPDKHW IMRYTGPMKP IHMEFTNMLQ RKRLQTLMSV DDSMETIYNM
300 301
LVETGELDNT YIVYTADHGY HIGQFGLVKG KSMPYEFDIR VPFYVRGPNV
350 351
EAGCLNPHIV LNIDLAPTIL DIAGLDIPAD MDGKSILKLL DTERPVNRFH
400 401
LKKKMRVWRD SFLVERGKLL HKRDNDKVDA QEENFLPKYQ RVKDLCQRAE
450 451
YQTACEQLGQ KWQCVEDATG KLKLHKCKGP MRLGGSRALS NLVPKYYGQG
500 501
SEACTCDSGD YKLSLAGRRK KLFKKKYKAS YVRSRSIRSV AIEVDGRVYH
550 551
VGLGDAAQPR NLTKRHWPGA PEDQDDKDGG DFSGTGGLPD YSAANPIKVT
600 601
HRCYILENDT VQCDLDLYKS LQAWKDHKLH IDHEIETLQN KIKNLREVRG
650 651
HLKKKRPEEC DCHKISYHTQ HKGRLKHRGS SLHPFRKGLQ EKDKVWLLRE
700 701
QKRKKKLRKL LKRLQNNDTC SMPGLTCFTH DNQHWQTAPF WTLGPFCACT
750 751
SANNNTYWCM RTINETHNFL FCEFATGFLE YFDLNTDPYQ LMNAVNTLDR
800 801
DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW
850 851
PEMKRPSSKS LGQLWEGWEG
870
Show the unformatted sequence. |
| Checksums: |
CRC64:74B1069CE2774D73
MD5:636bceadd767ff886ecc37aba2ea7c62
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.