Summary
This is the summary of UniProt entry GP116_HUMAN (Q8IZF2).
| Description: | Probable G-protein coupled receptor 116 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1346 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 21 |
| disorder | n/a | 45 | 51 |
| Pfam A | SEA | 166 | 266 |
| Pfam A | I-set | 278 | 367 |
| Pfam A | Ig_2 | 472 | 563 |
| Pfam B | Pfam-B_18859 | 841 | 939 |
| Pfam A | GPS | 950 | 997 |
| low_complexity | n/a | 994 | 1016 |
| transmembrane | n/a | 1007 | 1033 |
| Pfam A | 7tm_2 | 1010 | 1262 |
| transmembrane | n/a | 1054 | 1075 |
| transmembrane | n/a | 1095 | 1117 |
| transmembrane | n/a | 1129 | 1151 |
| transmembrane | n/a | 1171 | 1194 |
| low_complexity | n/a | 1171 | 1197 |
| transmembrane | n/a | 1214 | 1234 |
| low_complexity | n/a | 1224 | 1238 |
| transmembrane | n/a | 1246 | 1271 |
| low_complexity | n/a | 1329 | 1346 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IZF2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MKSPRRTTLC LMFIVIYSSK AALNWNYEST IHPLSLHEHE PAGEEALRQK
50 51
RAVATKSPTA EEYTVNIEIS FENASFLDPI KAYLNSLSFP IHGNNTDQIT
100 101
DILSINVTTV CRPAGNEIWC SCETGYGWPR ERCLHNLICQ ERDVFLPGHH
150 151
CSCLKELPPN GPFCLLQEDV TLNMRVRLNV GFQEDLMNTS SALYRSYKTD
200 201
LETAFRKGYG ILPGFKGVTV TGFKSGSVVV TYEVKTTPPS LELIHKANEQ
250 251
VVQSLNQTYK MDYNSFQAVT INESNFFVTP EIIFEGDTVS LVCEKEVLSS
300 301
NVSWRYEEQQ LEIQNSSRFS IYTALFNNMT SVSKLTIHNI TPGDAGEYVC
350 351
KLILDIFEYE CKKKIDVMPI QILANEEMKV MCDNNPVSLN CCSQGNVNWS
400 401
KVEWKQEGKI NIPGTPETDI DSSCSRYTLK ADGTQCPSGS SGTTVIYTCE
450 451
FISAYGARGS ANIKVTFISV ANLTITPDPI SVSEGQNFSI KCISDVSNYD
500 501
EVYWNTSAGI KIYQRFYTTR RYLDGAESVL TVKTSTREWN GTYHCIFRYK
550 551
NSYSIATKDV IVHPLPLKLN IMVDPLEATV SCSGSHHIKC CIEEDGDYKV
600 601
TFHTGSSSLP AAKEVNKKQV CYKHNFNASS VSWCSKTVDV CCHFTNAANN
650 651
SVWSPSMKLN LVPGENITCQ DPVIGVGEPG KVIQKLCRFS NVPSSPESPI
700 701
GGTITYKCVG SQWEEKRNDC ISAPINSLLQ MAKALIKSPS QDEMLPTYLK
750 751
DLSISIDKAE HEISSSPGSL GAIINILDLL STVPTQVNSE MMTHVLSTVN
800 801
VILGKPVLNT WKVLQQQWTN QSSQLLHSVE RFSQALQSGD SPPLSFSQTN
850 851
VQMSSMVIKS SHPETYQQRF VFPYFDLWGN VVIDKSYLEN LQSDSSIVTM
900 901
AFPTLQAILA QDIQENNFAE SLVMTTTVSH NTTMPFRISM TFKNNSPSGG
950 951
ETKCVFWNFR LANNTGGWDS SGCYVEEGDG DNVTCICDHL TSFSILMSPD
1000 1001
SPDPSSLLGI LLDIISYVGV GFSILSLAAC LVVEAVVWKS VTKNRTSYMR
1050 1051
HTCIVNIAAS LLVANTWFIV VAAIQDNRYI LCKTACVAAT FFIHFFYLSV
1100 1101
FFWMLTLGLM LFYRLVFILH ETSRSTQKAI AFCLGYGCPL AISVITLGAT
1150 1151
QPREVYTRKN VCWLNWEDTK ALLAFAIPAL IIVVVNITIT IVVITKILRP
1200 1201
SIGDKPCKQE KSSLFQISKS IGVLTPLLGL TWGFGLTTVF PGTNLVFHII
1250 1251
FAILNVFQGL FILLFGCLWD LKVQEALLNK FSLSRWSSQH SKSTSLGSST
1300 1301
PVFSMSSPIS RRFNNLFGKT GTYNVSTPEA TSSSLENSSS ASSLLN
1346
Show the unformatted sequence. |
| Checksums: |
CRC64:72A9D02B08218A60
MD5:2e93ca312f0496ded5151bbe6754b1e9
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.