Summary
This is the summary of UniProt entry PKN3_MOUSE (Q8K045).
| Description: | Serine/threonine-protein kinase N3 EC=2.7.11.13 |
| Source organism: |
Mus musculus (Mouse)
(NCBI taxonomy ID
10090)
View Pfam proteome data. |
| Length: | 878 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 56 |
| Pfam A | HR1 | 15 | 82 |
| coiled_coil | n/a | 54 | 74 |
| disorder | n/a | 58 | 59 |
| disorder | n/a | 61 | 65 |
| disorder | n/a | 67 | 68 |
| disorder | n/a | 72 | 101 |
| Pfam A | HR1 | 98 | 170 |
| disorder | n/a | 118 | 130 |
| disorder | n/a | 132 | 137 |
| low_complexity | n/a | 157 | 172 |
| disorder | n/a | 158 | 175 |
| Pfam A | HR1 | 171 | 242 |
| low_complexity | n/a | 182 | 194 |
| coiled_coil | n/a | 201 | 235 |
| disorder | n/a | 207 | 212 |
| low_complexity | n/a | 207 | 220 |
| low_complexity | n/a | 222 | 236 |
| Pfam B | Pfam-B_42882 | 244 | 302 |
| disorder | n/a | 307 | 309 |
| disorder | n/a | 458 | 478 |
| disorder | n/a | 486 | 525 |
| low_complexity | n/a | 528 | 537 |
| disorder | n/a | 529 | 536 |
| Pfam A | Pkinase | 548 | 807 |
| Pfam A | Pkinase_C | 827 | 874 |
| low_complexity | n/a | 842 | 858 |
| disorder | n/a | 848 | 850 |
| disorder | n/a | 852 | 853 |
| disorder | n/a | 855 | 856 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8K045. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MEHRKPGTGQ RAPKDEKEMV RRAIQKELKI KEGMENMRRV ATDRRHLGHV
50 51
QQLLRASNRR LEQLHGELRE LHAQVLLPAS AEPVTSEPQP RAEQSRARLS
100 101
EALHRQLQVE LKVKQGAENM IHTCASGTPK ERKLLAAAQQ MLKDSQLKVA
150 151
LLRMKISSLE SSGSPEPGPD LLAEELQHRL RVEAAVAAGA KNVVKLLGGQ
200 201
RMQDRKALAE AQAQLQESSQ KLDLLRLALE LLLERLPPTH SLRSRVTQEL
250 251
WMAMLGNPQP LGTLVKPIAL TGTLQVRLLG CKDLLVAVPG RSPMAVLAGS
300 301
PSESWLRTRS RQQRGGGELA SEVLAVLKVD NRVVGQTGWG LVAEKSWDQS
350 351
FIISLDRARE LEIGVHWRDW RQLCGVAFLK LEDFLDNACH QLSLSLVPQG
400 401
RLFAQVTFCE PVIERRPRLQ RQRCIFSKRR GRDFMRASQM NLSMAAWGRL
450 451
VMSLLPPCSS PNTASPPKGR PSTAVCGTPS AASPSNFLPM KTLSKEDTKP
500 501
PPKPPRLYLQ EPAPGTPCTK RPHMDPRPAV VPALAALSTR KPPRLQDFRC
550 551
LAVLGRGHFG KVLLVQYKGT GKYYAIKALK KQEVLGRDEI DSLYCEKRIL
600 601
ETVGRTGHPF LLSLLACLQT SSHACFVTEF LPGGDLMAQI HEDVFPEPQA
650 651
CFYLACVVLG LQFLHEKRII YRDLKLDNLL LDAQGFLKIA DFGLCKEGIG
700 701
FGDRTSTFCG TPEFLAPEVL TQEAYTRAVD WWGLGVLLYE MLVGECPFPG
750 751
DTEEEVFECI VSADVPCPHF LSVQGLELIQ KLLQKSPEKR LGAGERDAEE
800 801
IKVQPFFRTT NWQALLARTV QPPFVPTLCG PADLRYFEGE FTSLPPTLTP
850 851
PVSQSSLTAR QQAAFRDFDF VSEQFLES
878
Show the unformatted sequence. |
| Checksums: |
CRC64:F4DC174A6E89047D
MD5:43084a23aceba7f6dc9410cdf9667b47
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.