Summary
This is the summary of UniProt entry MES4_DROME (Q8MT36).
| Description: | Probable histone-lysine N-methyltransferase Mes-4 EC=2.1.1.43 |
| Source organism: |
Drosophila melanogaster (Fruit fly)
(NCBI taxonomy ID
7227)
View Pfam proteome data. |
| Length: | 1427 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 111 |
| low_complexity | n/a | 89 | 100 |
| disorder | n/a | 120 | 191 |
| low_complexity | n/a | 135 | 147 |
| low_complexity | n/a | 174 | 181 |
| disorder | n/a | 199 | 235 |
| low_complexity | n/a | 227 | 240 |
| disorder | n/a | 237 | 291 |
| disorder | n/a | 295 | 301 |
| disorder | n/a | 324 | 329 |
| disorder | n/a | 336 | 339 |
| low_complexity | n/a | 367 | 378 |
| Pfam A | PWWP | 393 | 512 |
| disorder | n/a | 424 | 427 |
| disorder | n/a | 432 | 435 |
| disorder | n/a | 485 | 486 |
| disorder | n/a | 536 | 551 |
| disorder | n/a | 553 | 561 |
| disorder | n/a | 566 | 575 |
| disorder | n/a | 577 | 578 |
| disorder | n/a | 582 | 632 |
| Pfam B | Pfam-B_22710 | 666 | 732 |
| disorder | n/a | 682 | 685 |
| disorder | n/a | 687 | 691 |
| low_complexity | n/a | 693 | 704 |
| disorder | n/a | 694 | 695 |
| disorder | n/a | 720 | 753 |
| low_complexity | n/a | 723 | 735 |
| disorder | n/a | 817 | 843 |
| disorder | n/a | 880 | 889 |
| disorder | n/a | 891 | 892 |
| Pfam A | PWWP | 1047 | 1137 |
| disorder | n/a | 1119 | 1122 |
| disorder | n/a | 1148 | 1163 |
| Pfam A | SET | 1245 | 1351 |
| disorder | n/a | 1275 | 1276 |
| disorder | n/a | 1398 | 1403 |
| low_complexity | n/a | 1402 | 1415 |
| disorder | n/a | 1408 | 1427 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8MT36. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MKLSTDAHSE IEGDAAHGNV LCNSASDSLT ATDEVAAGND ESVATEGDDV
50 51
EIPRDTNNST PVRLLDKPGQ NPVQNGAQPA AEESELESQR QTPVQKQQQQ
100 101
RVSMVNRKRD LINLQSALSP KYIGYANANS PTPLSDSDDT IRTTRRRVNQ
150 151
AAALNNSSAG ETLAHDNASP RTPGGGGGGG GDDSANQLLS KTYMSPIEKL
200 201
LIKNGASSPN STGFEAGSED LGIRPIVRKH VKRKMKRVPK AKVTLELDEK
250 251
NQQEVDEKSV KTEPIDEEVD RTDEAPTQEA QTTAISIKSE TEAEHKAAVD
300 301
VHIKQEDTIR LDIVNNPVES TSIVITEEPK DLEKSTEELA FALPLASSTE
350 351
VDLKSPPDLS STALATSIKS PSSVSIDSAK GLSIVTDPGW PTYQVGDLFW
400 401
GKVFSYCFWP CMVCPDPLGQ IVGNMPSHPQ RSSLDNANVP IQVHVRFFAD
450 451
NGRRNWIKPE NLLTFAGLKA FDDMREELRI KHGPKSAKYR QMVPKRTKVV
500 501
IWRQAIEEAQ AMTQIPYSDR LEKFYQTYEN VVTLNRQKRK RTKYMMQDTS
550 551
DVGSSLYDST DNLHNKQGTQ LLAVKRERSE SPFSPAFSPV KSKNEKRAKR
600 601
RKLSNGTEAD TGSNSMAVTP SQTETTVDSS AYENPEFRQL LSAVMEYVMM
650 651
NRSDEKVEKV LLSVVSNIWS LKQIQLRELE RDLASGEIEE PLGSSVVGRG
700 701
SGVGTIKRLS NRLMTMMVRR SMTPVVTPST TPAPSEPDRR LSEPPKTKKP
750 751
VNRPIEEVIE DILQLDSKYL FRGLSREPIC KYCYQAGSDL VRCSRTCSSW
800 801
LHADCLERKV TGAPMPKIGS RKALVIPPTS KSPSPDEDHV TADAKEVVAV
850 851
GTSLVCHECN VGEPEGCVIC HQVESPAVPS TPRKEDSSSH TPIEDKLLTC
900 901
SQPMCGKRFH TSCCKYWPQA SSSKHSARCP RHVCHTCVSD DPSGKFQQLG
950 951
SSKLAKCVRC PATYHQLSKC IPAGTQMLNT TNIICPRHNI AKADAHVNVL
1000 1001
WCYICVKGGE LVCCETCPIA VHAHCRNIPI KTNESYICEE CESGRLPLYG
1050 1051
EIVWAKFNNF RWWPAIILPP TEVPSNILKK AHGENDFVVR FFGTHDHGWI
1100 1101
SRRRVYLYIE GDTGDGHKTK SQLFRNYTTG VEEASRFLPI IKARRQEQDM
1150 1151
ERQSGNKLHP PPYVKIKTNK AVPPLRFSQN LEDLSTCNCL PVDEHPCGPE
1200 1201
AGCLNRMLFN ECNPEYCKAG SLCENRMFEQ RKSPRLEVVY MNERGFGLVN
1250 1251
REPIAVGDFV IEYVGEVINH AEFQRRMEQK QRDRDENYYF LGVEKDFIID
1300 1301
AGPKGNLARF MNHSCEPNCE TQKWTVNCIH RVGIFAIKDI PVNSELTFNY
1350 1351
LWDDLMNNSK KACFCGAKRC SGEIGGKLKD DAVKAHAKLK QMRRAKASAV
1400 1401
RIHVKPKKTP KVKHISADDE PMDAKDE
1427
Show the unformatted sequence. |
| Checksums: |
CRC64:FB6EFD62E814BEF3
MD5:6a072c387235dcc3f2517e08bb3c1130
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.