Summary
This is the summary of UniProt entry DOCK8_HUMAN (Q8NF50).
| Description: | Dedicator of cytokinesis protein 8 |
| Source organism: |
Homo sapiens (Human) |
| Length: | 2099 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | DUF3398 | 69 | 164 |
| low_complexity | n/a | 83 | 96 |
| disorder | n/a | 105 | 109 |
| disorder | n/a | 156 | 158 |
| disorder | n/a | 165 | 172 |
| coiled_coil | n/a | 219 | 239 |
| disorder | n/a | 221 | 229 |
| disorder | n/a | 252 | 253 |
| disorder | n/a | 255 | 256 |
| low_complexity | n/a | 322 | 336 |
| low_complexity | n/a | 421 | 438 |
| disorder | n/a | 532 | 535 |
| Pfam A | DOCK-C2 | 555 | 739 |
| low_complexity | n/a | 785 | 802 |
| disorder | n/a | 867 | 870 |
| disorder | n/a | 907 | 915 |
| low_complexity | n/a | 940 | 956 |
| disorder | n/a | 946 | 957 |
| low_complexity | n/a | 1002 | 1019 |
| Pfam B | Pfam-B_8896 | 1082 | 1218 |
| low_complexity | n/a | 1122 | 1137 |
| low_complexity | n/a | 1166 | 1177 |
| disorder | n/a | 1245 | 1247 |
| Pfam B | Pfam-B_3144 | 1291 | 1614 |
| low_complexity | n/a | 1370 | 1383 |
| disorder | n/a | 1375 | 1376 |
| disorder | n/a | 1379 | 1386 |
| disorder | n/a | 1409 | 1411 |
| low_complexity | n/a | 1696 | 1707 |
| Pfam A | Ded_cyto | 1882 | 2059 |
| low_complexity | n/a | 2045 | 2057 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8NF50. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MATLPSAERR AFALKINRYS SAEIRKQFTL PPNLGQYHRQ SISTSGFPSL
50 51
QLPQFYDPVE PVDFEGLLMT HLNSLDVQLA QELGDFTDDD LDVVFTPKEC
100 101
RTLQPSLPEE GVELDPHVRD CVQTYIREWL IVNRKNQGSP EICGFKKTGS
150 151
RKDFHKTLPK QTFESETLEC SEPAAQAGPR HLNVLCDVSG KGPVTACDFD
200 201
LRSLQPDKRL ENLLQQVSAE DFEKQNEEAR RTNRQAELFA LYPSVDEEDA
250 251
VEIRPVPECP KEHLGNRILV KLLTLKFEIE IEPLFASIAL YDVKERKKIS
300 301
ENFHCDLNSD QFKGFLRAHT PSVAASSQAR SAVFSVTYPS SDIYLVVKIE
350 351
KVLQQGEIGD CAEPYTVIKE SDGGKSKEKI EKLKLQAESF CQRLGKYRMP
400 401
FAWAPISLSS FFNVSTLERE VTDVDSVVGR SSVGERRTLA QSRRLSERAL
450 451
SLEENGVGSN FKTSTLSVSS FFKQEGDRLS DEDLFKFLAD YKRSSSLQRR
500 501
VKSIPGLLRL EISTAPEIIN CCLTPEMLPV KPFPENRTRP HKEILEFPTR
550 551
EVYVPHTVYR NLLYVYPQRL NFVNKLASAR NITIKIQFMC GEDASNAMPV
600 601
IFGKSSGPEF LQEVYTAVTY HNKSPDFYEE VKIKLPAKLT VNHHLLFTFY
650 651
HISCQQKQGA SVETLLGYSW LPILLNERLQ TGSYCLPVAL EKLPPNYSMH
700 701
SAEKVPLQNP PIKWAEGHKG VFNIEVQAVS SVHTQDNHLE KFFTLCHSLE
750 751
SQVTFPIRVL DQKISEMALE HELKLSIICL NSSRLEPLVL FLHLVLDKLF
800 801
QLSVQPMVIA GQTANFSQFA FESVVAIANS LHNSKDLSKD QHGRNCLLAS
850 851
YVHYVFRLPE VQRDVPKSGA PTALLDPRSY HTYGRTSAAA VSSKLLQARV
900 901
MSSSNPDLAG THSAADEEVK NIMSSKIADR NCSRMSYYCS GSSDAPSSPA
950 951
APRPASKKHF HEELALQMVV STGMVRETVF KYAWFFFELL VKSMAQHVHN
1000 1001
MDKRDSFRRT RFSDRFMDDI TTIVNVVTSE IAALLVKPQK ENEQAEKMNI
1050 1051
SLAFFLYDLL SLMDRGFVFN LIRHYCSQLS AKLSNLPTLI SMRLEFLRIL
1100 1101
CSHEHYLNLN LFFMNADTAP TSPCPSISSQ NSSSCSSFQD QKIASMFDLT
1150 1151
SEYRQQHFLT GLLFTELAAA LDAEGEGISK VQRKAVSAIH SLLSSHDLDP
1200 1201
RCVKPEVKVK IAALYLPLVG IILDALPQLC DFTVADTRRY RTSGSDEEQE
1250 1251
GAGAINQNVA LAIAGNNFNL KTSGIVLSSL PYKQYNMLNA DTTRNLMICF
1300 1301
LWIMKNADQS LIRKWIADLP STQLNRILDL LFICVLCFEY KGKQSSDKVS
1350 1351
TQVLQKSRDV KARLEEALLR GEGARGEMMR RRAPGNDRFP GLNENLRWKK
1400 1401
EQTHWRQANE KLDKTKAELD QEALISGNLA TEAHLIILDM QENIIQASSA
1450 1451
LDCKDSLLGG VLRVLVNSLN CDQSTTYLTH CFATLRALIA KFGDLLFEEE
1500 1501
VEQCFDLCHQ VLHHCSSSMD VTRSQACATL YLLMRFSFGA TSNFARVKMQ
1550 1551
VTMSLASLVG RAPDFNEEHL RRSLRTILAY SEEDTAMQMT PFPTQVEELL
1600 1601
CNLNSILYDT VKMREFQEDP EMLMDLMYRI AKSYQASPDL RLTWLQNMAE
1650 1651
KHTKKKCYTE AAMCLVHAAA LVAEYLSMLE DHSYLPVGSV SFQNISSNVL
1700 1701
EESVVSEDTL SPDEDGVCAG QYFTESGLVG LLEQAAELFS TGGLYETVNE
1750 1751
VYKLVIPILE AHREFRKLTL THSKLQRAFD SIVNKDHKRM FGTYFRVGFF
1800 1801
GSKFGDLDEQ EFVYKEPAIT KLPEISHRLE AFYGQCFGAE FVEVIKDSTP
1850 1851
VDKTKLDPNK AYIQITFVEP YFDEYEMKDR VTYFEKNFNL RRFMYTTPFT
1900 1901
LEGRPRGELH EQYRRNTVLT TMHAFPYIKT RISVIQKEEF VLTPIEVAIE
1950 1951
DMKKKTLQLA VAINQEPPDA KMLQMVLQGS VGATVNQGPL EVAQVFLAEI
2000 2001
PADPKLYRHH NKLRLCFKEF IMRCGEAVEK NKRLITADQR EYQQELKKNY
2050 2051
NKLKENLRPM IERKIPELYK PIFRVESQKR DSFHRSSFRK CETQLSQGS
2099
Show the unformatted sequence. |
| Checksums: |
CRC64:AF651C26E2D8E73E
MD5:ea6b2a4766520f4865c2fba0912d53a6
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