Summary
This is the summary of UniProt entry OTU7A_HUMAN (Q8TE49).
| Description: | OTU domain-containing protein 7A EC=3.4.19.12 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 926 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_42735 | 1 | 27 |
| disorder | n/a | 1 | 3 |
| Pfam A | UBA_4 | 28 | 66 |
| disorder | n/a | 30 | 32 |
| disorder | n/a | 46 | 47 |
| disorder | n/a | 74 | 103 |
| Pfam A | OTU | 205 | 368 |
| disorder | n/a | 250 | 251 |
| low_complexity | n/a | 260 | 269 |
| disorder | n/a | 282 | 291 |
| disorder | n/a | 293 | 296 |
| disorder | n/a | 381 | 386 |
| disorder | n/a | 411 | 412 |
| disorder | n/a | 448 | 516 |
| Pfam B | Pfam-B_8213 | 465 | 546 |
| low_complexity | n/a | 469 | 507 |
| disorder | n/a | 520 | 523 |
| low_complexity | n/a | 524 | 544 |
| disorder | n/a | 531 | 612 |
| low_complexity | n/a | 556 | 578 |
| low_complexity | n/a | 580 | 592 |
| Pfam B | Pfam-B_10899 | 613 | 670 |
| disorder | n/a | 636 | 637 |
| disorder | n/a | 639 | 642 |
| disorder | n/a | 651 | 779 |
| low_complexity | n/a | 676 | 691 |
| low_complexity | n/a | 724 | 757 |
| disorder | n/a | 782 | 783 |
| disorder | n/a | 787 | 792 |
| disorder | n/a | 795 | 817 |
| disorder | n/a | 820 | 821 |
| disorder | n/a | 825 | 852 |
| low_complexity | n/a | 826 | 844 |
| disorder | n/a | 862 | 866 |
| disorder | n/a | 869 | 883 |
| low_complexity | n/a | 912 | 925 |
| disorder | n/a | 921 | 926 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TE49. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MVSSVLPNPT SAECWAALLH DPMTLDMDAV LSDFVRSTGA EPGLARDLLE
50 51
GKNWDLTAAL SDYEQLRQVH TANLPHVFNE GRGPKQPERE PQPGHKVERP
100 101
CLQRQDDIAQ EKRLSRGISH ASSAIVSLAR SHVASECNNE QFPLEMPIYT
150 151
FQLPDLSVYS EDFRSFIERD LIEQATMVAL EQAGRLNWWS TVCTSCKRLL
200 201
PLATTGDGNC LLHAASLGMW GFHDRDLVLR KALYTMMRTG AEREALKRRW
250 251
RWQQTQQNKE EEWEREWTEL LKLASSEPRT HFSKNGGTGG GVDNSEDPVY
300 301
ESLEEFHVFV LAHILRRPIV VVADTMLRDS GGEAFAPIPF GGIYLPLEVP
350 351
PNRCHCSPLV LAYDQAHFSA LVSMEQRDQQ REQAVIPLTD SEHKLLPLHF
400 401
AVDPGKDWEW GKDDNDNARL AHLILSLEAK LNLLHSYMNV TWIRIPSETR
450 451
APLAQPESPT ASAGEDVQSL ADSLDSDRDS VCSNSNSNNG KNGKDKEKEK
500 501
QRKEKDKTRA DSVANKLGSF SKTLGIKLKK NMGGLGGLVH GKMGRANSAN
550 551
GKNGDSAERG KEKKAKSRKG SKEESGASAS TSPSEKTTPS PTDKAAGASP
600 601
AEKGGGPRGD AWKYSTDVKL SLNILRAAMQ GERKFIFAGL LLTSHRHQFH
650 651
EEMIGYYLTS AQERFSAEQE QRRRDAATAA AAAAAAAAAT AKRPPRRPET
700 701
EGVPVPERAS PGPPTQLVLK LKERPSPGPA AGRAARAAAG GTASPGGGAR
750 751
RASASGPVPG RSPPAPARQS VIHVQASGAR DEACAPAVGA LRPCATYPQQ
800 801
NRSLSSQSYS PARAAALRTV NTVESLARAV PGALPGAAGT AGAAEHKSQT
850 851
YTNGFGALRD GLEFADADAP TARSNGECGR GGPGPVQRRC QRENCAFYGR
900 901
AETEHYCSYC YREELRRRRE ARGARP
926
Show the unformatted sequence. |
| Checksums: |
CRC64:6E4623C2EB2C8058
MD5:aa00a15a9c57f08bd62ae376f1acb792
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| UBA_4 | 28 - 66 | 2L2D | A | 28 - 66 | Jmol AstexViewer SPICE |