Summary
This is the summary of UniProt entry IPO4_HUMAN (Q8TEX9).
| Description: | Importin-4 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1081 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| low_complexity | n/a | 6 | 15 |
| Pfam A | IBN_N | 24 | 90 |
| low_complexity | n/a | 32 | 51 |
| low_complexity | n/a | 60 | 72 |
| low_complexity | n/a | 117 | 133 |
| low_complexity | n/a | 218 | 235 |
| low_complexity | n/a | 282 | 297 |
| disorder | n/a | 303 | 322 |
| low_complexity | n/a | 308 | 327 |
| Pfam A | HEAT_2 | 392 | 549 |
| Pfam B | Pfam-B_15255 | 574 | 675 |
| low_complexity | n/a | 627 | 659 |
| disorder | n/a | 634 | 635 |
| disorder | n/a | 637 | 640 |
| disorder | n/a | 642 | 658 |
| disorder | n/a | 810 | 827 |
| low_complexity | n/a | 814 | 823 |
| low_complexity | n/a | 835 | 862 |
| Pfam A | HEAT_EZ | 913 | 968 |
| low_complexity | n/a | 938 | 949 |
| low_complexity | n/a | 1042 | 1052 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TEX9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MESAGLEQLL RELLLPDTER IRRATEQLQI VLRAPAALPA LCDLLASAAD
50 51
PQIRQFAAVL TRRRLNTRWR RLAAEQRESL KSLILTALQR ETEHCVSLSL
100 101
AQLSATIFRK EGLEAWPQLL QLLQHSTHSP HSPEREMGLL LLSVVVTSRP
150 151
EAFQPHHREL LRLLNETLGE VGSPGLLFYS LRTLTTMAPY LSTEDVPLAR
200 201
MLVPKLIMAM QTLIPIDEAK ACEALEALDE LLESEVPVIT PYLSEVLTFC
250 251
LEVARNVALG NAIRIRILCC LTFLVKVKSK ALLKNRLLPP LLHTLFPIVA
300 301
AEPPPGQLDP EDQDSEEEEL EIELMGETPK HFAVQVVDML ALHLPPEKLC
350 351
PQLMPMLEEA LRSESPYQRK AGLLVLAVLS DGAGDHIRQR LLPPLLQIVC
400 401
KGLEDPSQVV RNAALFALGQ FSENLQPHIS SYSREVMPLL LAYLKSVPLG
450 451
HTHHLAKACY ALENFVENLG PKVQPYLPEL MECMLQLLRN PSSPRAKELA
500 501
VSALGAIATA AQASLLPYFP AIMEHLREFL LTGREDLQPV QIQSLETLGV
550 551
LARAVGEPMR PLAEECCQLG LGLCDQVDDP DLRRCTYSLF AALSGLMGEG
600 601
LAPHLEQITT LMLLSLRSTE GIVPQYDGSS SFLLFDDESD GEEEEELMDE
650 651
DVEEEDDSEI SGYSVENAFF DEKEDTCAAV GEISVNTSVA FLPYMESVFE
700 701
EVFKLLECPH LNVRKAAHEA LGQFCCALHK ACQSCPSEPN TAALQAALAR
750 751
VVPSYMQAVN RERERQVVMA VLEALTGVLR SCGTLTLKPP GRLAELCGVL
800 801
KAVLQRKTAC QDTDEEEEEE DDDQAEYDAM LLEHAGEAIP ALAAAAGGDS
850 851
FAPFFAGFLP LLVCKTKQGC TVAEKSFAVG TLAETIQGLG AASAQFVSRL
900 901
LPVLLSTAQE ADPEVRSNAI FGMGVLAEHG GHPAQEHFPK LLGLLFPLLA
950 951
RERHDRVRDN ICGALARLLM ASPTRKPEPQ VLAALLHALP LKEDLEEWVT
1000 1001
IGRLFSFLYQ SSPDQVIDVA PELLRICSLI LADNKIPPDT KAALLLLLTF
1050 1051
LAKQHTDSFQ AALGSLPVDK AQELQAVLGL S
1081
Show the unformatted sequence. |
| Checksums: |
CRC64:36D11AF0D6DA8B1E
MD5:64fe95e2ae257f54765da665036b6dea
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.