Summary
This is the summary of UniProt entry SCFD1_HUMAN (Q8WVM8).
| Description: | Sec1 family domain-containing protein 1 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 642 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 18 |
| low_complexity | n/a | 2 | 13 |
| Pfam A | Sec1 | 43 | 636 |
| low_complexity | n/a | 131 | 144 |
| disorder | n/a | 298 | 314 |
| disorder | n/a | 337 | 338 |
| coiled_coil | n/a | 338 | 358 |
| disorder | n/a | 341 | 343 |
| disorder | n/a | 345 | 346 |
| disorder | n/a | 359 | 360 |
| disorder | n/a | 566 | 569 |
| disorder | n/a | 579 | 581 |
Show or hide domain scores.
Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
Note: it can take a few seconds for this image to be generated and loaded.
Show sources update panel.
Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8WVM8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MAAAAAATAA AAASIRERQT VALKRMLNFN VPHIKNSTGE PVWKVLIYDR
50 51
FGQDIISPLL SVKELRDMGI TLHLLLHSDR DPIPDVPAVY FVMPTEENID
100 101
RMCQDLRNQL YESYYLNFIS AISRSKLEDI ANAALAASAV TQVAKVFDQY
150 151
LNFITLEDDM FVLCNQNKEL VSYRAINRPD ITDTEMETVM DTIVDSLFCF
200 201
FVTLGAVPII RCSRGTAAEM VAVKLDKKLR ENLRDARNSL FTGDTLGAGQ
250 251
FSFQRPLLVL VDRNIDLATP LHHTWTYQAL VHDVLDFHLN RVNLEESSGV
300 301
ENSPAGARPK RKNKKSYDLT PVDKFWQKHK GSPFPEVAES VQQELESYRA
350 351
QEDEVKRLKS IMGLEGEDEG AISMLSDNTA KLTSAVSSLP ELLEKKRLID
400 401
LHTNVATAVL EHIKARKLDV YFEYEEKIMS KTTLDKSLLD IISDPDAGTP
450 451
EDKMRLFLIY YISTQQAPSE ADLEQYKKAL TDAGCNLNPL QYIKQWKAFT
500 501
KMASAPASYG STTTKPMGLL SRVMNTGSQF VMEGVKNLVL KQQNLPVTRI
550 551
LDNLMEMKSN PETDDYRYFD PKMLRGNDSS VPRNKNPFQE AIVFVVGGGN
600 601
YIEYQNLVDY IKGKQGKHIL YGCSELFNAT QFIKQLSQLG QK
642
Show the unformatted sequence. |
| Checksums: |
CRC64:0340FB9F05CD24CE
MD5:ecc52cc390b9ae9fc751f894dd623118
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

