Summary
This is the summary of UniProt entry SC5A5_HUMAN (Q92911).
| Description: | Sodium/iodide cotransporter |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 643 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| transmembrane | n/a | 12 | 34 |
| Pfam A | SSF | 47 | 452 |
| transmembrane | n/a | 54 | 75 |
| transmembrane | n/a | 87 | 110 |
| transmembrane | n/a | 131 | 152 |
| transmembrane | n/a | 164 | 181 |
| transmembrane | n/a | 188 | 206 |
| transmembrane | n/a | 242 | 261 |
| transmembrane | n/a | 282 | 307 |
| transmembrane | n/a | 342 | 371 |
| transmembrane | n/a | 392 | 413 |
| low_complexity | n/a | 404 | 416 |
| transmembrane | n/a | 419 | 437 |
| transmembrane | n/a | 444 | 466 |
| low_complexity | n/a | 444 | 463 |
| disorder | n/a | 505 | 506 |
| disorder | n/a | 510 | 511 |
| transmembrane | n/a | 528 | 549 |
| disorder | n/a | 585 | 602 |
| disorder | n/a | 626 | 643 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q92911. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MEAVETGERP TFGAWDYGVF ALMLLVSTGI GLWVGLARGG QRSAEDFFTG
50 51
GRRLAALPVG LSLSASFMSA VQVLGVPSEA YRYGLKFLWM CLGQLLNSVL
100 101
TALLFMPVFY RLGLTSTYEY LEMRFSRAVR LCGTLQYIVA TMLYTGIVIY
150 151
APALILNQVT GLDIWASLLS TGIICTFYTA VGGMKAVVWT DVFQVVVMLS
200 201
GFWVVLARGV MLVGGPRQVL TLAQNHSRIN LMDFNPDPRS RYTFWTFVVG
250 251
GTLVWLSMYG VNQAQVQRYV ACRTEKQAKL ALLINQVGLF LIVSSAACCG
300 301
IVMFVFYTDC DPLLLGRISA PDQYMPLLVL DIFEDLPGVP GLFLACAYSG
350 351
TLSTASTSIN AMAAVTVEDL IKPRLRSLAP RKLVIISKGL SLIYGSACLT
400 401
VAALSSLLGG GVLQGSFTVM GVISGPLLGA FILGMFLPAC NTPGVLAGLG
450 451
AGLALSLWVA LGATLYPPSE QTMRVLPSSA ARCVALSVNA SGLLDPALLP
500 501
ANDSSRAPSS GMDASRPALA DSFYAISYLY YGALGTLTTV LCGALISCLT
550 551
GPTKRSTLAP GLLWWDLARQ TASVAPKEEV AILDDNLVKG PEELPTGNKK
600 601
PPGFLPTNED RLFFLGQKEL EGAGSWTPCV GHDGGRDQQE TNL
643
Show the unformatted sequence. |
| Checksums: |
CRC64:02D361A27B2FDA43
MD5:0ce8d28c66b7161de38363757e1eb712
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.