Summary
This is the summary of UniProt entry SH3K1_HUMAN (Q96B97).
| Description: | SH3 domain-containing kinase-binding protein 1 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 665 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | SH3_9 | 6 | 54 |
| disorder | n/a | 59 | 81 |
| disorder | n/a | 85 | 90 |
| low_complexity | n/a | 91 | 102 |
| Pfam A | SH3_9 | 105 | 153 |
| low_complexity | n/a | 121 | 139 |
| disorder | n/a | 150 | 152 |
| disorder | n/a | 158 | 160 |
| disorder | n/a | 162 | 203 |
| low_complexity | n/a | 177 | 195 |
| disorder | n/a | 244 | 265 |
| Pfam A | SH3_9 | 274 | 324 |
| disorder | n/a | 318 | 320 |
| disorder | n/a | 322 | 639 |
| low_complexity | n/a | 337 | 343 |
| low_complexity | n/a | 377 | 387 |
| low_complexity | n/a | 392 | 407 |
| low_complexity | n/a | 491 | 512 |
| low_complexity | n/a | 550 | 582 |
| coiled_coil | n/a | 602 | 654 |
| disorder | n/a | 645 | 646 |
| disorder | n/a | 649 | 650 |
| disorder | n/a | 652 | 653 |
| disorder | n/a | 660 | 664 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q96B97. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MVEAIVEFDY QAQHDDELTI SVGEIITNIR KEDGGWWEGQ INGRRGLFPD
50 51
NFVREIKKEM KKDPLTNKAP EKPLHEVPSG NSLLSSETIL RTNKRGERRR
100 101
RRCQVAFSYL PQNDDELELK VGDIIEVVGE VEEGWWEGVL NGKTGMFPSN
150 151
FIKELSGESD ELGISQDEQL SKSSLRETTG SESDGGDSSS TKSEGANGTV
200 201
ATAAIQPKKV KGVGFGDIFK DKPIKLRPRS IEVENDFLPV EKTIGKKLPA
250 251
TTATPDSSKT EMDSRTKSKD YCKVIFPYEA QNDDELTIKE GDIVTLINKD
300 301
CIDVGWWEGE LNGRRGVFPD NFVKLLPPDF EKEGNRPKKP PPPSAPVIKQ
350 351
GAGTTERKHE IKKIPPERPE MLPNRTEEKE RPEREPKLDL QKPSVPAIPP
400 401
KKPRPPKTNS LSRPGALPPR RPERPVGPLT HTRGDSPKID LAGSSLSGIL
450 451
DKDLSDRSND IDLEGFDSVV SSTEKLSHPT TSRPKATGRR PPSQSLTSSS
500 501
LSSPDIFDSP SPEEDKEEHI SLAHRGVDAS KKTSKTVTIS QVSDNKASLP
550 551
PKPGTMAAGG GGPAPLSSAA PSPLSSSLGT AGHRANSPSL FGTEGKPKME
600 601
PAASSQAAVE ELRTQVRELR SIIETMKDQQ KREIKQLLSE LDEEKKIRLR
650 651
LQMEVNDIKK ALQSK
665
Show the unformatted sequence. |
| Checksums: |
CRC64:3BD350FCDB14BD4C
MD5:807c6652426e2c865fff6af40bc7a729
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| SH3_9 | 105 - 153 | 2O2O | A | 105 - 153 | Jmol AstexViewer SPICE |
| 274 - 324 | 2K6D | A | 274 - 324 | Jmol AstexViewer SPICE | |
| 2K9G | A | 274 - 324 | Jmol AstexViewer SPICE | ||
| 2YDL | A | 274 - 324 | Jmol AstexViewer SPICE | ||
| 6 - 54 | 2BZ8 | A | 6 - 54 | Jmol AstexViewer SPICE | |
| B | 6 - 54 | Jmol AstexViewer SPICE |