Summary
This is the summary of UniProt entry PF21A_HUMAN (Q96BD5).
| Description: | PHD finger protein 21A |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 680 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_7050 | 1 | 349 |
| disorder | n/a | 23 | 40 |
| coiled_coil | n/a | 30 | 57 |
| disorder | n/a | 58 | 60 |
| disorder | n/a | 69 | 124 |
| low_complexity | n/a | 84 | 112 |
| disorder | n/a | 149 | 150 |
| disorder | n/a | 154 | 156 |
| disorder | n/a | 170 | 187 |
| disorder | n/a | 189 | 192 |
| disorder | n/a | 211 | 222 |
| disorder | n/a | 224 | 262 |
| low_complexity | n/a | 240 | 261 |
| disorder | n/a | 265 | 289 |
| disorder | n/a | 291 | 293 |
| disorder | n/a | 307 | 371 |
| disorder | n/a | 377 | 405 |
| disorder | n/a | 411 | 482 |
| Pfam A | AT_hook | 425 | 436 |
| Pfam A | PHD | 490 | 535 |
| Pfam B | Pfam-B_15568 | 536 | 649 |
| low_complexity | n/a | 559 | 571 |
| coiled_coil | n/a | 562 | 600 |
| disorder | n/a | 569 | 575 |
| disorder | n/a | 581 | 585 |
| disorder | n/a | 608 | 609 |
| disorder | n/a | 636 | 637 |
| disorder | n/a | 639 | 678 |
| low_complexity | n/a | 650 | 671 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q96BD5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MELQTLQEAL KVEIQVHQKL VAQMKQDPQN ADLKKQLHEL QAKITALSEK
50 51
QKRVVEQLRK NLIVKQEQPD KFQIQPLPQS ENKLQTAQQQ PLQQLQQQQQ
100 101
YHHHHAQQSA AASPNLTASQ KTVTTASMIT TKTLPLVLKA ATATMPASVV
150 151
GQRPTIAMVT AINSQKAVLS TDVQNTPVNL QTSSKVTGPG AEAVQIVAKN
200 201
TVTLVQATPP QPIKVPQFIP PPRLTPRPNF LPQVRPKPVA QNNIPIAPAP
250 251
PPMLAAPQLI QRPVMLTKFT PTTLPTSQNS IHPVRVVNGQ TATIAKTFPM
300 301
AQLTSIVIAT PGTRLAGPQT VQLSKPSLEK QTVKSHTETD EKQTESRTIT
350 351
PPAAPKPKRE ENPQKLAFMV SLGLVTHDHL EEIQSKRQER KRRTTANPVY
400 401
SGAVFEPERK KSAVTYLNST MHPGTRKRGR PPKYNAVLGF GALTPTSPQS
450 451
SHPDSPENEK TETTFTFPAP VQPVSLPSPT STDGDIHEDF CSVCRKSGQL
500 501
LMCDTCSRVY HLDCLDPPLK TIPKGMWICP RCQDQMLKKE EAIPWPGTLA
550 551
IVHSYIAYKA AKEEEKQKLL KWSSDLKQER EQLEQKVKQL SNSISKCMEM
600 601
KNTILARQKE MHSSLEKVKQ LIRLIHGIDL SKPVDSEATV GAISNGPDCT
650 651
PPANAATSTP APSPSSQSCT ANCNQGEETK
680
Show the unformatted sequence. |
| Checksums: |
CRC64:C7AF87EB2984A796
MD5:c88f19456df9b5384b31bf498087afcc
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| PHD | 490 - 535 | 2PUY | A | 490 - 535 | Jmol AstexViewer SPICE |
| B | 490 - 535 | Jmol AstexViewer SPICE | |||
| 2YQL | A | 11 - 56 | Jmol AstexViewer SPICE |