Summary
This is the summary of UniProt entry CECR2_HUMAN (Q9BXF3).
| Description: | Cat eye syndrome critical region protein 2 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1484 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_13010 | 1 | 329 |
| low_complexity | n/a | 4 | 14 |
| disorder | n/a | 170 | 215 |
| low_complexity | n/a | 194 | 209 |
| disorder | n/a | 217 | 241 |
| disorder | n/a | 258 | 259 |
| disorder | n/a | 286 | 313 |
| disorder | n/a | 316 | 319 |
| disorder | n/a | 321 | 330 |
| low_complexity | n/a | 325 | 340 |
| coiled_coil | n/a | 326 | 364 |
| Pfam B | Pfam-B_20164 | 331 | 419 |
| disorder | n/a | 337 | 341 |
| low_complexity | n/a | 346 | 369 |
| disorder | n/a | 352 | 360 |
| disorder | n/a | 389 | 391 |
| low_complexity | n/a | 391 | 406 |
| disorder | n/a | 414 | 424 |
| disorder | n/a | 426 | 430 |
| Pfam A | Bromodomain | 443 | 526 |
| disorder | n/a | 533 | 539 |
| disorder | n/a | 542 | 777 |
| low_complexity | n/a | 553 | 571 |
| low_complexity | n/a | 605 | 614 |
| low_complexity | n/a | 755 | 766 |
| disorder | n/a | 779 | 781 |
| disorder | n/a | 791 | 1141 |
| Pfam B | Pfam-B_18245 | 800 | 968 |
| low_complexity | n/a | 975 | 986 |
| low_complexity | n/a | 995 | 1007 |
| low_complexity | n/a | 1085 | 1100 |
| disorder | n/a | 1150 | 1213 |
| low_complexity | n/a | 1204 | 1218 |
| disorder | n/a | 1215 | 1220 |
| disorder | n/a | 1228 | 1344 |
| low_complexity | n/a | 1238 | 1253 |
| disorder | n/a | 1346 | 1416 |
| disorder | n/a | 1420 | 1484 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9BXF3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MCPEEGGAAG LGELRSWWEV PAIAHFCSLF RTAFRLPDFE IEELEAALHR
50 51
DDVEFISDLI ACLLQGCYQR RDITPQTFHS YLEDIINYRW ELEEGKPNPL
100 101
REASFQDLPL RTRVEILHRL CDYRLDADDV FDLLKGLDAD SLRVEPLGED
150 151
NSGALYWYFY GTRMYKEDPV QGKSNGELSL SRESEGQKNV SSIPGKTGKR
200 201
RGRPPKRKKL QEEILLSEKQ EENSLASEPQ TRHGSQGPGQ GTWWLLCQTE
250 251
EEWRQVTESF RERTSLRERQ LYKLLSEDFL PEICNMIAQK GKRPQRTKAE
300 301
LHPRWMSDHL SIKPVKQEET PVLTRIEKQK RKEEEEERQI LLAVQKKEQE
350 351
QMLKEERKRE LEEKVKAVEG MCSVRVVWRG ACLSTSRPVD RAKRRKLREE
400 401
RAWLLAQGKE LPPELSHLDP NSPMREEKKT KDLFELDDDF TAMYKVLDVV
450 451
KAHKDSWPFL EPVDESYAPN YYQIIKAPMD ISSMEKKLNG GLYCTKEEFV
500 501
NDMKTMFRNC RKYNGESSEY TKMSDNLERC FHRAMMKHFP GEDGDTDEEF
550 551
WIREDEKREK RRSRAGRSGG SHVWTRSRDP EGSSRKQQPM ENGGKSLPPT
600 601
RRAPSSGDDQ SSSSTQPPRE VGTSNGRGFS HPLHCGGTPS QAPFLNQMRP
650 651
AVPGTFGPLR GSDPATLYGS SGVPEPHPGE PVQQRQPFTM QPPVGINSLR
700 701
GPRLGTPEEK QMCGGLTHLS NMGPHPGSLQ LGQISGPSQD GSMYAPAQFQ
750 751
PGFIPPRHGG APARPPDFPE SSEIPPSHMY RSYKYLNRVH SAVWNGNHGA
800 801
TNQGPLGPDE KPHLGPGPSH QPRTLGHVMD SRVMRPPVPP NQWTEQSGFL
850 851
PHGVPSSGYM RPPCKSAGHR LQPPPVPAPS SLFGAPAQAL RGVQGGDSMM
900 901
DSPEMIAMQQ LSSRVCPPGV PYHPHQPAHP RLPGPFPQVA HPMSVTVSAP
950 951
KPALGNPGRA PENSEAQEPE NDQAEPLPGL EEKPPGVGTS EGVYLTQLPH
1000 1001
PTPPLQTDCT RQSSPQERET VGPELKSSSS ESADNCKAMK GKNPWPSDSS
1050 1051
YPGPAAQGCV RDLSTVADRG ALSENGVIGE ASPCGSEGKG LGSSGSEKLL
1100 1101
CPRGRTLQET MPCTGQNAAT PPSTDPGLTG GTVSQFPPLY MPGLEYPNSA
1150 1151
AHYHISPGLQ GVGPVMGGKS PASHPQHFPP RGFQSNHPHS GGFPRYRPPQ
1200 1201
GMRYSYHPPP QPSYHHYQRT PYYACPQSFS DWQRPLHPQG SPSGPPASQP
1250 1251
PPPRSLFSDK NAMASLQGCE TLNAALTSPT RMDAVAAKVP NDGQNPGPEE
1300 1301
EKLDESMERP ESPKEFLDLD NHNAATKRQS SLSASEYLYG TPPPLSSGMG
1350 1351
FGSSAFPPHS VMLQTGPPYT PQRPASHFQP RAYSSPVAAL PPHHPGATQP
1400 1401
NGLSQEGPIY RCQEEGLGHF QAVMMEQIGT RSGIRGPFQE MYRPSGMQMH
1450 1451
PVQSQASFPK TPTAATSQEE VPPHKPPTLP LDQS
1484
Show the unformatted sequence. |
| Checksums: |
CRC64:8680DB16A0B90D0D
MD5:a3c4581186f6636922c3ec470bae85ee
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Bromodomain | 443 - 526 | 3NXB | A | 443 - 526 | Jmol AstexViewer SPICE |
| B | 443 - 526 | Jmol AstexViewer SPICE |