Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GSTO2_HUMAN (Q9H4Y5)

Summary

This is the summary of UniProt entry GSTO2_HUMAN (Q9H4Y5).

Description: Glutathione S-transferase omega-2 EC=2.5.1.18 EC=1.8.5.1 EC=1.20.4.2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 243 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 14
Pfam A GST_N_3 26 101
Pfam A GST_C_2 91 206

Show or hide domain scores.

Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

Note: it can take a few seconds for this image to be generated and loaded.

Loading feature alignment...

Show sources update panel.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9H4Y5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGDATRTLG KGSQPPGPVP EGLIRIYSMR FCPYSHRTRL VLKAKDIRHE
50
51
VVNINLRNKP EWYYTKHPFG HIPVLETSQC QLIYESVIAC EYLDDAYPGR
100
101
KLFPYDPYER ARQKMLLELF CKVPHLTKEC LVALRCGREC TNLKAALRQE
150
151
FSNLEEILEY QNTTFFGGTC ISMIDYLLWP WFERLDVYGI LDCVSHTPAL
200
201
RLWISAMKWD PTVCALLMDK SIFQGFLNLY FQNNPNAFDF GLC       
243
 

Show the unformatted sequence.

Checksums:
CRC64:45A959432BCF490A
MD5:d3d23fa9d88e8fa22a11a567948d7957

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
GST_C_2 91 - 206 3Q18 A 91 - 206 Jmol AstexViewer SPICE
B 91 - 206 Jmol AstexViewer SPICE
3Q19 A 91 - 206 Jmol AstexViewer SPICE
B 91 - 206 Jmol AstexViewer SPICE
3QAG A 91 - 206 Jmol AstexViewer SPICE
GST_N_3 26 - 101 3Q18 A 26 - 101 Jmol AstexViewer SPICE
B 26 - 101 Jmol AstexViewer SPICE
3Q19 A 26 - 101 Jmol AstexViewer SPICE
B 26 - 101 Jmol AstexViewer SPICE
3QAG A 26 - 101 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.