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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: KC1G1_HUMAN (Q9HCP0)

Summary

This is the summary of UniProt entry KC1G1_HUMAN (Q9HCP0).

Description: Casein kinase I isoform gamma-1 EC=2.7.11.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 422 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 27
low_complexity n/a 29 36
disorder n/a 31 32
Pfam A Pkinase 44 315
disorder n/a 265 266
Pfam A CK1gamma_C 331 392
disorder n/a 340 394
low_complexity n/a 397 403
low_complexity n/a 405 416
disorder n/a 419 422

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9HCP0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDHPSREKDE RQRTTKPMAQ RSAHCSRPSG SSSSSGVLMV GPNFRVGKKI
50
51
GCGNFGELRL GKNLYTNEYV AIKLEPIKSR APQLHLEYRF YKQLGSAGEG
100
101
LPQVYYFGPC GKYNAMVLEL LGPSLEDLFD LCDRTFTLKT VLMIAIQLLS
150
151
RMEYVHSKNL IYRDVKPENF LIGRQGNKKE HVIHIIDFGL AKEYIDPETK
200
201
KHIPYREHKS LTGTARYMSI NTHLGKEQSR RDDLEALGHM FMYFLRGSLP
250
251
WQGLKADTLK ERYQKIGDTK RNTPIEALCE NFPEEMATYL RYVRRLDFFE
300
301
KPDYEYLRTL FTDLFEKKGY TFDYAYDWVG RPIPTPVGSV HVDSGASAIT
350
351
RESHTHRDRP SQQQPLRNQV VSSTNGELNV DDPTGAHSNA PITAHAEVEV
400
401
VEEAKCCCFF KRKRKKTAQR HK                              
422
 

Show the unformatted sequence.

Checksums:
CRC64:B875922349B97645
MD5:83fdf9dc3039c42339bc941a0847a1c3

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CK1gamma_C 331 - 339 2CMW A 331 - 339 Jmol AstexViewer SPICE
Pkinase 45 - 315 2CMW A 45 - 315 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.